| Literature DB >> 3770955 |
Abstract
The alpha-hemolysin structural gene, hly+, previously cloned, insertionally inactivated, and introduced into the chromosome by allele replacement (M.O. O'Reilly, J.C.S. De Azavedo, S. Kennedy, and T.J. Foster, Microb. Pathog. 1:125-138, 1986), was shown by protoplast fusion and transformation to be in the gene order purC-hly-uraB-omega[chr::Tn916]1101-thrB on the chromosome of Staphylococcus aureus NCTC 8325. This location is clearly distinct from that of the agr determinant, a regulatory gene affecting several extracellular proteins, including alpha-hemolysin, located between tmn and ilv.Entities:
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Year: 1986 PMID: 3770955 PMCID: PMC260204 DOI: 10.1128/iai.54.2.593-596.1986
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441