Literature DB >> 3770201

Donor and acceptor splice signals within an exon of the human fibronectin gene: a new type of differential splicing.

K Vibe-Pedersen, S Magnusson, F E Baralle.   

Abstract

We have sequenced that area of a human fibronectin gene clone which codes for a connecting strand separating the last two areas of the type III homology. The gene has a complex exon with two 'AG' acceptor sites. One of these can be used (exon subdivision). In addition 93 basepairs inside the exon are sometimes spliced out as an intron. This is the third differential splicing found in the fibronectin gene transcript and it represents a new type of differential splicing.

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Year:  1986        PMID： 3770201     DOI： 10.1016/0014-5793(86)81506-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  9 in total

1.  Splicing of constitutive upstream introns is essential for the recognition of intra-exonic suboptimal splice sites in the thrombopoietin gene.

Authors:  M Romano; R Marcucci; F E Baralle
Journal:  Nucleic Acids Res       Date:  2001-02-15       Impact factor: 16.971

2.  Cell-type-specific expression of alternatively spliced human fibronectin IIICS mRNAs.

Authors:  R P Hershberger; L A Culp
Journal:  Mol Cell Biol       Date:  1990-02       Impact factor: 4.272

3.  Modulation of fibronectin gene expression in human mononuclear phagocytes.

Authors:  K Yamauchi; Y Martinet; R G Crystal
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

Review 4.  New insights into form and function of fibronectin splice variants.

Authors:  E S White; F E Baralle; A F Muro
Journal:  J Pathol       Date:  2008-09       Impact factor: 7.996

5.  Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature.

Authors:  M J Elices; V Tsai; D Strahl; A S Goel; V Tollefson; T Arrhenius; E A Wayner; F C Gaeta; J D Fikes; G S Firestein
Journal:  J Clin Invest       Date:  1994-01       Impact factor: 14.808

6.  Multiple sites of alternative splicing of the rat fibronectin gene transcript.

Authors:  J E Schwarzbauer; R S Patel; D Fonda; R O Hynes
Journal:  EMBO J       Date:  1987-09       Impact factor: 11.598

7.  The CS1 segment of fibronectin is involved in human OSCC pathogenesis by mediating OSCC cell spreading, migration, and invasion.

Authors:  Pachiyappan Kamarajan; Angeles Garcia-Pardo; Nisha J D'Silva; Yvonne L Kapila
Journal:  BMC Cancer       Date:  2010-06-25       Impact factor: 4.430

Review 8.  Role of pseudoexons and pseudointrons in human cancer.

Authors:  Maurizio Romano; Emanuele Buratti; Diana Baralle
Journal:  Int J Cell Biol       Date:  2013-09-24

9.  IIICS de novo glycosylated fibronectin as a marker for invasiveness in urothelial carcinoma of the urinary bladder (UBC).

Authors:  Petra Richter; Kerstin Junker; Marcus Franz; Angela Berndt; Christiane Geyer; Mieczyslaw Gajda; Hartwig Kosmehl; Alexander Berndt; Heiko Wunderlich
Journal:  J Cancer Res Clin Oncol       Date:  2008-04-03       Impact factor: 4.553
  9 in total

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