Literature DB >> 3770136

Immunoquantitation of some cytochrome P-450 isozymes in liver microsomes from streptozotocin-diabetic rats.

E Rouer, P Beaune, J P Leroux.   

Abstract

Streptozotocin-diabetes in rats leads to a decrease of cytochrome P-450 UT-A (the major form in control rats) and an increase of cytochrome P-450 PB-B (the major one induced by phenobarbital treatment) in liver microsomes. The increased benzphetamine-N-demethylase activity can be related to the induction of cytochrome P-450 PB-B.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3770136     DOI： 10.1007/bf01941293

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  The metabolism of drugs by liver microsomes from alloxan-diabetic rats.

Authors:  R L DIXON; L G HART; J R FOUTS
Journal:  J Pharmacol Exp Ther       Date:  1961-07       Impact factor: 4.030

2.  Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.

Authors:  R Kato; J R Gillette
Journal:  J Pharmacol Exp Ther       Date:  1965-11       Impact factor: 4.030

3.  Immunochemical characterization of some monooxygenase activities in liver microsomes from untreated and phenobarbital-treated rats.

Authors:  E Le Provost; J P Flinois; P Beaune; J P Leroux
Journal:  Biochem Biophys Res Commun       Date:  1981-07-30       Impact factor: 3.575

4.  Estimation of isozymes of microsomal cytochrome P-450 in rats, rabbits, and humans using immunochemical staining coupled with sodium dodecyl sulfate-polyacrylamide gel electrophoresis.

Authors:  F P Guengerich; P Wang; N K Davidson
Journal:  Biochemistry       Date:  1982-03-30       Impact factor: 3.162

5.  Effect of diabetes on rat liver cytochrome P-450. Evidence for a unique diabetes-dependent rat liver cytochrome P-450.

Authors:  M R Past; D E Cook
Journal:  Biochem Pharmacol       Date:  1982-10-15       Impact factor: 5.858

6.  A cytochrome P-450 multigene family. Characterization of a gene activated by phenobarbital administration.

Authors:  M Atchison; M Adesnik
Journal:  J Biol Chem       Date:  1983-09-25       Impact factor: 5.157

7.  Differential effects of diabetes on microsomal metabolism of various substrates. Comparison of streptozotocin and spontaneously diabetic Wistar rats.

Authors:  B L Warren; R Pak; M Finlayson; L Gontovnick; G Sunahara; G D Bellward
Journal:  Biochem Pharmacol       Date:  1983-01-15       Impact factor: 5.858

8.  Drug metabolism in diabetic isolated perfused rat liver.

Authors:  D E Cook; M R Past
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1979-05

9.  Purification and characterization of liver microsomal cytochromes p-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes isolated from rats treated with phenobarbital or beta-naphthoflavone.

Authors:  F P Guengerich; G A Dannan; S T Wright; M V Martin; L S Kaminsky
Journal:  Biochemistry       Date:  1982-11-09       Impact factor: 3.162

10.  Study of benzphetamine-N-demethylase in streptozotocin-diabetic mice and rats: evidence for the induction of catalytically and immunologically specific forms of cytochrome P450.

Authors:  E Rouer; E Le Provost; J P Leroux
Journal:  Biochimie       Date:  1983 Nov-Dec       Impact factor: 4.079
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.