Literature DB >> 3769769

Bradycardia due to trihexyphenidyl hydrochloride.

R Blumensohn, G Razoni, A Shalev, H Munitz.   

Abstract

A chronic schizophrenic patient was treated with an anticholinergic drug, trihexyphenidyl hydrochloride. The patient developed, paradoxically, sinus bradycardia. The reaction was specific to trihexyphenidyl and not to other anticholinergic drugs. This antidyskinetic drug is widely used in clinical psychiatric practice and physicians should be aware of this side effect.

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Year:  1986        PMID: 3769769     DOI: 10.1177/106002808602001012

Source DB:  PubMed          Journal:  Drug Intell Clin Pharm        ISSN: 0012-6578


  2 in total

1.  Accelerated structure-based design of chemically diverse allosteric modulators of a muscarinic G protein-coupled receptor.

Authors:  Yinglong Miao; Dahlia Anne Goldfeld; Ee Von Moo; Patrick M Sexton; Arthur Christopoulos; J Andrew McCammon; Celine Valant
Journal:  Proc Natl Acad Sci U S A       Date:  2016-09-06       Impact factor: 11.205

2.  Trihexyphenidyl induced malignant hyperthermia in a patient with Parkinson's disease complicated with pneumonia: A case report.

Authors:  Jun Zhao; Gang Xu; Congrui Feng; Yuluo Chen; Yanhong Kang; Feng Liu; Wei Ma
Journal:  Medicine (Baltimore)       Date:  2020-05       Impact factor: 1.889

  2 in total

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