Literature DB >> 376911

Post-operative long-term adjuvant immunochemotherapy with mitomycin-C, PSK and FT-207 in gastric cancer patients.

T Hattori, M Niimoto, T Koh, A Nakano, M Oride, W Takiyama, K Nishimawari.   

Abstract

Long-term adjuvant immunochemotherapy carried out on the gastrectomized patients with stomach cancer was reported. The protocol comprises the administration of large-dose of Mitomycin-C (20+10) mg just after gastrectomy and the long-term administration of PSK, FT-207 or (PSK+FT-207). Almost no side effects were observed. According to the studies on the immunological parameters, the increased reactions in PPD skin test and lymphocyte blastogenesis induced by PHA and PWM were observed remarkably in group (P+F) 3 or 6 months after gastrectomy. As for the survival rate, group (P+F) showed the most preferable results at one year in stage IV, at two years in stage III and at three years in all the stages, respectively after gastrectomy.

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Year:  1979        PMID： 376911     DOI： 10.1007/bf02468845

Source DB:  PubMed          Journal:  Jpn J Surg        ISSN： 0047-1909


  8 in total

1.  Restoration of antibody-forming capacities by PS-K in tumor-bearing mice.

Authors:  K Nomoto; C Yoshikumi; K Matsunaga; T Fujii; K Takeya
Journal:  Gan       Date:  1975-08

2.  LARGE-DOSE ADMINISTRATION OF MITOMYCIN-C DURING GASTRECTOMY FOLLOWED BY HOMOLOGOUS BONE MARROW TRANSPLANTATION.

Authors:  T HATTORI; I ITO; K HIRATA
Journal:  Gan       Date:  1964-06

3.  Lymphocyte responsiveness to phytohemagglutinin (PHA) and serum inhibitory effect in patients with gastric cancer.

Authors:  T Toge; H Ikeda; N Senoo; M Niimoto; T Hattori
Journal:  Jpn J Surg       Date:  1976-12

4.  Five-year survival rate of gastric cancer patients treated by gastrectomy, large dose of mitomycin-C, and-or allogeneic bone marrow transplantation.

Authors:  T Hattori; A Mori; K Hirata; I Ito
Journal:  Gan       Date:  1972-10

5.  Protein-bound polysaccharide preparation, PS-K, effective against mouse sarcoma-180 and rat ascites hepatoma AH-13 by oral use.

Authors:  S Tsukagoshi; F Ophashi
Journal:  Gan       Date:  1974-12

6.  Results of combined treatment in patients with cancer of the stomach: palliative gastrectomy, large-dose Mitomycin-C, and bone marrow transplantation.

Authors:  T Hattori; I Ito; K Hirata; T Iizuka; K Abe
Journal:  Gan       Date:  1966-10

7.  The general rules for The gastric cancer study in surgery.

Authors: 
Journal:  Jpn J Surg       Date:  1973-03

8.  Postoperative long term chemotherapy for advanced gastric cancer.

Authors:  N Kaibara; K Soejima; T Nakamura; K Inokuchi
Journal:  Jpn J Surg       Date:  1976-06
  8 in total
  11 in total

1.  Postoperative adjuvant chemotherapy for gastric cancer, the second report. Analysis of data on 2873 patients followed for five years.

Authors:  T Hattori; K Inokuchi; T Taguchi; O Abe
Journal:  Jpn J Surg       Date:  1986-05

2.  A randomized trial of chemoimmunotherapy of acute nonlymphocytic leukemia in adults using a protein-bound polysaccharide preparation.

Authors:  R Ohno; K Yamada; T Masaoka; T Ohshima; I Amaki; Y Hirota; N Horikoshi; A Horiuchi; K Imai; I Kimura
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

3.  Effects of Levamisole in adjuvant immunochemotherapy for gastric cancer; a prospective randomized controlled study.

Authors:  T Hattori; M Niimoto; T Toge; M Oride; A Nakao; K Yoshinaka
Journal:  Jpn J Surg       Date:  1983-11

4.  Combination chemoimmunotherapy for advanced gastric carcinoma.

Authors:  T Akiyoshi; M Kawaguchi; S Arinaga; S Miyazaki; F Koba; T Wada; H Tsuji
Journal:  Jpn J Surg       Date:  1984-05

5.  Clinical evaluation of schizophyllan adjuvant immunochemotherapy for patients with resectable gastric cancer--a randomized controlled trial.

Authors:  S Fujimoto; H Furue; T Kimura; T Kondo; K Orita; T Taguchi; K Yoshida; N Ogawa
Journal:  Jpn J Surg       Date:  1984-07

6.  Late results of postoperative long-term cancer chemotherapy for the gastric cancer patients subjected to curative resection.

Authors:  T Kano; R Kumashiro; H Masuda; R Tamada; K Inokuchi
Journal:  Jpn J Surg       Date:  1983-03

7.  Late results of postoperative long term cancer chemotherapy for advanced carcinoma of the stomach.

Authors:  T Kano; R Kumashiro; R Tamada; Y Kodama; K Inokuchi
Journal:  Jpn J Surg       Date:  1981

8.  Combined effect of prophylactic lymphadenectomy and long term combination chemotherapy for curatively resected carcinoma of the stomach.

Authors:  Y Kodama; T Kano; R Tamada; R Kumashiro; T Okamura; K Inokuchi
Journal:  Jpn J Surg       Date:  1982

9.  Postoperative adjuvant immunochemotherapy with mitomycin C, futraful and PSK for gastric cancer. An analysis of data on 579 patients followed for five years.

Authors:  M Niimoto; T Hattori; R Tamada; K Sugimachi; K Inokuchi; N Ogawa
Journal:  Jpn J Surg       Date:  1988-11

10.  Protective effect of biological response modifiers on murine cytomegalovirus infection.

Authors:  K Ebihara; Y Minamishima
Journal:  J Virol       Date:  1984-07       Impact factor: 5.103
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