| Literature DB >> 3768669 |
Abstract
A culture system was developed to study intrinsic oscillations within rat suprachiasmatic nuclei for long periods of time. After isolation in static organ cultures, individual rat suprachiasmatic explants released vasopressin in a circadian fashion for at least 4 cycles. This finding suggests that the suprachiasmatic nucleus contains one or more self-sustained circadian oscillators, and that this method of measuring circadian rhythms from individual suprachiasmatic organ cultures may prove to be a valuable model for elucidating the physiology and biochemistry of mammalian circadian pacemakers.Entities:
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Year: 1986 PMID： 3768669 DOI： 10.1016/0006-8993(86)90119-8
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252