Literature DB >> 3768248

Theophylline pharmacokinetics after intravenous infusion with ethylenediamine or sodium glycinate.

J Caldwell, A H Staib, I A Cotgreave, M Siebert-Weigel.   

Abstract

Six healthy volunteers received two theophylline preparations by short intravenous infusion, at weekly intervals in a randomized cross-over design. The solubilizer was ethylenediamine or sodium glycinate. Plasma concentrations of theophylline and ethylenediamine were measured by h.p.l.c. for up to 24 h after dosing. The pharmacokinetics of theophylline did not show any significant intra-subject variation associated with the solubilizing agent used.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3768248      PMCID： PMC1401136          DOI： 10.1111/j.1365-2125.1986.tb02899.x

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN： 0306-5251            Impact factor:   4.335


  16 in total

1.  High-pressure liquid chromatographic and spectrophotometric assays for theophylline in biological fluids.

Authors:  W J Jusko; A Poliszczuk
Journal:  Am J Hosp Pharm       Date:  1976-11

Review 2.  Clinical pharmacokinetics of theophylline.

Authors:  R I Ogilvie
Journal:  Clin Pharmacokinet       Date:  1978 Jul-Aug       Impact factor: 6.447

3.  Comparative plasma pharmacokinetics of theophylline and ethylenediamine after the administration of aminophylline to man.

Authors:  I A Cotgreave; J Caldwell
Journal:  J Pharm Pharmacol       Date:  1983-06       Impact factor: 3.765

4.  Current concepts. Slow-release theophylline rationale and basis for product selection.

Authors:  M Weinberger; L Hendeles
Journal:  N Engl J Med       Date:  1983-03-31       Impact factor: 91.245

5.  The pharmacokinetics of lysine theophylline, a new soluble theophylline, in human volunteers.

Authors:  A Johnston; M E Aldhous; A Hedges; K Weerasuriya; A Freedman; P Turner
Journal:  Postgrad Med J       Date:  1983-02       Impact factor: 2.401

6.  Intraindividual variability in theophylline pharmacokinetics: statistical verification in 39 of 60 healthy young adults.

Authors:  R A Upton; J F Thiercelin; T W Guentert; S M Wallace; J R Powell; L Sansom; S Riegelman
Journal:  J Pharmacokinet Biopharm       Date:  1982-04

7.  A metabolic and pharmacokinetic comparison of theophylline and aminophylline (theophylline ethylenediamine).

Authors:  T J Monks; R L Smith; J Caldwell
Journal:  J Pharm Pharmacol       Date:  1981-02       Impact factor: 3.765

Review 8.  Ethylenediamine, profile of a sensitizing excipient.

Authors:  J Zuidema
Journal:  Pharm Weekbl Sci       Date:  1985-08-23

9.  Studies on aminophylline disposition I. A rapid and sensitive HPLC assay for ethylenediamine in plasma and urine.

Authors:  I A Cotgreave; J Caldwell
Journal:  Biopharm Drug Dispos       Date:  1983 Jan-Mar       Impact factor: 1.627

10.  Comparative pharmacokinetics of theophylline and aminophylline in man.

Authors:  A Aslaksen; O M Bakke; T Vigander
Journal:  Br J Clin Pharmacol       Date:  1981-03       Impact factor: 4.335
View more
  2 in total

1.  Measurement of theophylline absorption from different regions of the gastro-intestinal tract using a remote controlled drug delivery device.

Authors:  A H Staib; D Loew; S Harder; E H Graul; R Pfab
Journal:  Eur J Clin Pharmacol       Date:  1986       Impact factor: 2.953

2.  Theophylline and ethylenediamine pharmacokinetics following administration of aminophylline to septic patients with multiorgan failure.

Authors:  P Toft; L Heslet; M Hansen; N A Klitgaard
Journal:  Intensive Care Med       Date:  1991       Impact factor: 17.440
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.