Literature DB >> 3767347

Cefuroxime axetil for treatment of uncomplicated gonorrhea.

A Gottlieb, J Mills.   

Abstract

Oral cefuroxime axetil (1 g) plus probenecid cured 29 of 30 urethral and 6 of 6 rectal gonococcal infections in men; alone the drug cured 22 of 23 urethral and 4 of 6 rectal infections. No toxicity was observed. Cefuroxime axetil alone is effective for urethral gonorrhea in males; rectal gonorrhea probably requires additional probenecid.

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Year:  1986        PMID： 3767347      PMCID： PMC180547          DOI： 10.1128/AAC.30.2.333

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  13 in total

1.  Penicillinase-producing Neisseria gonorrhoeae isolates from different localities in south east Asia. Susceptibility to 15 antibiotics.

Authors:  W S Ng; P Y Chau; J Ling; P Echeverria; R Rockhill; K Arnold
Journal:  Br J Vener Dis       Date:  1983-08

2.  Influence of inoculum size on comparative susceptibilities of penicillinase-positive and -negative Neisseria gonorrhoeae to 31 antimicrobial agents.

Authors:  W H Hall; B J Opfer
Journal:  Antimicrob Agents Chemother       Date:  1984-08       Impact factor: 5.191

3.  Distribution of auxotypes and correlation to antibiotic susceptibility of 169 recent clinical Neisseria gonorrhoeae isolates from Munich.

Authors:  G Ruckdeschel; U Neubert; H C Korting
Journal:  Arch Dermatol Res       Date:  1983       Impact factor: 3.017

4.  Pharmacology of Cefuroxime as the 1-acetoxyethyl ester in volunteers.

Authors:  S M Harding; P E Williams; J Ayrton
Journal:  Antimicrob Agents Chemother       Date:  1984-01       Impact factor: 5.191

5.  The absolute bioavailability of oral cefuroxime axetil in male and female volunteers after fasting and after food.

Authors:  P E Williams; S M Harding
Journal:  J Antimicrob Chemother       Date:  1984-02       Impact factor: 5.790

6.  Bioavailability and metabolism of talampicillin.

Authors:  K H Jones; P F Langley; L J Lees
Journal:  Chemotherapy       Date:  1978       Impact factor: 2.544

7.  Cefuroxime, thiamphenicol, spectinomycin, and penicillin G in uncomplicated infections due to penicillinase-producing strains of Neisseria gonorrhoeae.

Authors:  T E Tupasi; L B Crisologo; C A Torres; O V Calubiran; I de Jesus
Journal:  Br J Vener Dis       Date:  1983-06

Review 8.  Cefuroxime: mechanisms of action, antimicrobial activity, pharmacokinetics, clinical applications, adverse reactions and therapeutic indications.

Authors:  B Gold; W J Rodriguez
Journal:  Pharmacotherapy       Date:  1983 Mar-Apr       Impact factor: 4.705

9.  Comparative in vitro activity of cefodizime, ceftazidime, aztreonam, and other selected antimicrobial agents against Neisseria gonorrhoeae.

Authors:  M Y Khan; R P Gruninger; S M Nelson; S R Obaid
Journal:  Antimicrob Agents Chemother       Date:  1983-03       Impact factor: 5.191

10.  Single-dose cefuroxime axetil in the treatment of uncomplicated gonorrhea: a controlled trial.

Authors:  R C Reichman; F S Nolte; S M Wolinsky; C A Greisberger; M A Trupei; J Nitzkin
Journal:  Sex Transm Dis       Date:  1985 Oct-Dec       Impact factor: 2.830
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  9 in total

1.  Review of the pharmacology, pharmacokinetics, and clinical use of cephalosporins.

Authors:  D Kalman; S L Barriere
Journal:  Tex Heart Inst J       Date:  1990

2.  Cefuroxime axetil to treat gonorrhea.

Authors:  R P Das; K Jones; A J Robinson; D J Timmins
Journal:  Genitourin Med       Date:  1988-12

Review 3.  The future of new oral antibiotics including the quinolones.

Authors:  M G Bergeron
Journal:  CMAJ       Date:  1988-01-01       Impact factor: 8.262

Review 4.  Cefuroxime axetil: an updated review of its use in the management of bacterial infections.

Authors:  L J Scott; D Ormrod; K L Goa
Journal:  Drugs       Date:  2001       Impact factor: 9.546

5.  Comparison of single-dose cefuroxime axetil with ciprofloxacin in treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing Neisseria gonorrhoeae strains.

Authors:  E M Thorpe; J R Schwebke; E W Hook; A Rompalo; W M McCormack; K L Mussari; G C Giguere; J J Collins
Journal:  Antimicrob Agents Chemother       Date:  1996-12       Impact factor: 5.191

6.  Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women.

Authors:  L M Baddour; R S Gibbs; G Mertz; D M Cocchetto; R C Noble
Journal:  Antimicrob Agents Chemother       Date:  1989-06       Impact factor: 5.191

7.  Prepackaged therapy for urethritis: the "MSTOP" experience in Cameroon.

Authors:  F Crabbé; J P Tchupo; T Manchester; T Gruber-Tapsoba; D Mugrditchian; J Timyan; G Goodridge; C Cheta; M Laga; G Dallabetta
Journal:  Sex Transm Infect       Date:  1998-08       Impact factor: 3.519

Review 8.  Cefuroxime axetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  C M Perry; R N Brogden
Journal:  Drugs       Date:  1996-07       Impact factor: 9.546

9.  Cefuroxime axetil (ceftin): a brief review.

Authors:  R D Leder; D S Carson
Journal:  Infect Dis Obstet Gynecol       Date:  1997
  9 in total

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