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Literature DB >> 3766836

The delivery and uptake of nicotine from an aerosol rod.

D W Sepkovic, S G Colosimo, C M Axelrad, J D Adams, N J Haley.

Abstract

Nicotine aerosol rods were assessed for their possible usefulness as substitutes for cigarettes. Under standard FTC conditions, the per puff delivery of the aerosol rod averaged 0.3 micrograms nicotine/puff after 10 puffs and 6.4 micrograms nicotine/puff after 60 puffs. After puffing on the rods, no nicotine was detected in the plasma or urine of seven subjects.

Entities: Chemical

Mesh：

Substances：
Aerosols
Nicotine
Cotinine

Year: 1986 PMID： 3766836 PMCID： PMC1646724 DOI： 10.2105/ajph.76.11.1343

Source DB: PubMed Journal: Am J Public Health ISSN： 0090-0036 Impact factor: 9.308

9 in total

1. Nicotine-containing chewing gum as an anti-smoking aid.

Authors: B Brantmark; P Ohlin; H Westling
Journal: Psychopharmacologia Date: 1973-07-19

2. Nitrosamines in cigarette smoke condensate.

Authors: A McCormick; M J Nicholson; M A Baylis; J G Underwood
Journal: Nature Date: 1973-07-27 Impact factor: 49.962

3. Retention of cigarette smoke components in human lungs.

Authors: T Dalhamn; M L Edfors; R Rylander
Journal: Arch Environ Health Date: 1968-11

4. Nasal nicotine solution: a potential aid to giving up smoking?

Authors: M A Russell; M J Jarvis; C Feyerabend; O Fernö
Journal: Br Med J (Clin Res Ed) Date: 1983-02-26

5. Cigarette smoking as a risk for cardiovascular disease III: Biochemical effects with higher nicotine yield cigarettes.

Authors: D W Sepkovic; N J Haley; C M Axelrad; E L Wynder
Journal: Addict Behav Date: 1983 Impact factor: 3.913

6. Disposition kinetics and effects of intravenous nicotine.

Authors: J Rosenberg; N L Benowitz; P Jacob; K M Wilson
Journal: Clin Pharmacol Ther Date: 1980-10 Impact factor: 6.875

7. Nicotine and its metabolites. Radioimmunoassays for nicotine and cotinine.

Authors: J J Langone; H B Gjika; H Van Vunakis
Journal: Biochemistry Date: 1973-11-20 Impact factor: 3.162

8. Transdermal administration of nicotine.

Authors: J E Rose; M E Jarvik; K D Rose
Journal: Drug Alcohol Depend Date: 1984-05 Impact factor: 4.492

9. Cigarette smoking as a risk for cardiovascular disease V: Biochemical parameters with increased and decreased nicotine content cigarettes.

Authors: D W Sepkovic; K Parker; C M Axelrad; N J Haley; E L Wynder
Journal: Addict Behav Date: 1984 Impact factor: 3.913