Literature DB >> 3761968

[Local treatment with diclofenac-Na eyedrops in diseases of the anterior eye segment].

H van Husen.   

Abstract

The nonsteroid anti-inflammatory drug (NSAID) diclofenac-sodium, in the galenic form of an eye drop solution (0.1%), has been tested in an open clinical trial in the following indications: episcleritis (30 patients), limbal corneal ulcer (9 patients), hay-fever conjunctivitis and/or conjunctivitis phlyctaenulosa (11 patients). The result of this clinical trial has shown that diclofenac-sodium eye drop solution fulfills all the requirements of a well-tolerated and effective NSAID. The application of diclofenac-sodium eye drop solution (3-5 times daily) resulted in a clear-cut reduction in the use of eye drops containing steroids and its prominent analgesic effect was impressive. Although a slight, transient burning sensation was noticed by a few patients shortly after instillation, no local or systemic adverse reactions were observed.

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Year:  1986        PMID: 3761968     DOI: 10.1055/s-2008-1050730

Source DB:  PubMed          Journal:  Klin Monbl Augenheilkd        ISSN: 0023-2165            Impact factor:   0.700


  3 in total

Review 1.  The emerging roles of topical non-steroidal anti-inflammatory agents in ophthalmology.

Authors:  P Koay
Journal:  Br J Ophthalmol       Date:  1996-05       Impact factor: 4.638

2.  Preservative-free diclofenac sodium 0.1% for vernal keratoconjunctivitis.

Authors:  Gennaro D'Angelo; Alessandro Lambiase; Magdalena Cortes; Roberto Sgrulletta; Roberta Pasqualetti; Ambra Lamagna; Stefano Bonini
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2003-02-15       Impact factor: 3.117

Review 3.  Ocular diclofenac. A review of its pharmacology and clinical use in cataract surgery, and potential in other inflammatory ocular conditions.

Authors:  K L Goa; P Chrisp
Journal:  Drugs Aging       Date:  1992 Nov-Dec       Impact factor: 3.923

  3 in total

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