Literature DB >> 3760826

Monoclonal antibodies against the glycoproteins of mumps virus: fusion inhibition by anti-HN monoclonal antibody.

M Tsurudome, A Yamada, M Hishiyama, Y Ito.   

Abstract

Six monoclonal antibodies (MAbs) against the haemagglutinin-neuraminidase (HN) protein and three against the fusion (F) protein of mumps virus were obtained. Anti-HN MAbs were classified into three antigen-specific groups in competitive binding assays. All of the anti-HN MAbs showed virus-neutralizing and haemolysis-inhibiting activities and inhibited fusion from without (FFWO). Three of them inhibited fusion from within (FFWI) and the cell-to-cell spread of infection. The most effective MAb in inhibiting FFWI possessed neuraminidase-inhibiting activity and little haemagglutination-inhibiting activity. All anti-F MAbs inhibited virus-induced haemolysis but none of them inhibited FFWO, FFWI or the cell-to-cell spread of infection.

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Year:  1986        PMID： 3760826     DOI： 10.1099/0022-1317-67-10-2259

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  16 in total

1.  Biological activity of paramyxovirus fusion proteins: factors influencing formation of syncytia.

Authors:  C M Horvath; R G Paterson; M A Shaughnessy; R Wood; R A Lamb
Journal:  J Virol       Date:  1992-07       Impact factor: 5.103

2.  Characterizations of the human parainfluenza type 2 virus gene encoding the L protein and the intergenic sequences.

Authors:  M Kawano; K Okamoto; H Bando; K Kondo; M Tsurudome; H Komada; M Nishio; Y Ito
Journal:  Nucleic Acids Res       Date:  1991-05-25       Impact factor: 16.971

3.  Function of small hydrophobic proteins of paramyxovirus.

Authors:  Rebecca L Wilson; Sandra M Fuentes; Ping Wang; Erica C Taddeo; Alicia Klatt; Andrew J Henderson; Biao He
Journal:  J Virol       Date:  2006-02       Impact factor: 5.103

4.  Immunological relationships between parainfluenza virus type 4 and other paramyxoviruses studied by use of monoclonal antibodies.

Authors:  H Komada; E Klippmark; C Orvell; R E Randall; Y Ito; E Norrby
Journal:  Arch Virol       Date:  1991       Impact factor: 2.574

5.  Identification of an amino acid that defines the fusogenicity of mumps virus.

Authors:  K Tanabayashi; K Takeuchi; K Okazaki; M Hishiyama; A Yamada
Journal:  J Virol       Date:  1993-05       Impact factor: 5.103

Review 6.  Role of sialic acid-containing molecules in paramyxovirus entry into the host cell: a minireview.

Authors:  Enrique Villar; Isabel Muñoz Barroso
Journal:  Glycoconj J       Date:  2006-02       Impact factor: 2.916

7.  Mumps Virus Is Released from the Apical Surface of Polarized Epithelial Cells, and the Release Is Facilitated by a Rab11-Mediated Transport System.

Authors:  Hiroshi Katoh; Yuichiro Nakatsu; Toru Kubota; Masafumi Sakata; Makoto Takeda; Minoru Kidokoro
Journal:  J Virol       Date:  2015-09-16       Impact factor: 5.103

8.  Fusion regulation proteins on the cell surface: isolation and characterization of monoclonal antibodies which enhance giant polykaryocyte formation in Newcastle disease virus-infected cell lines of human origin.

Authors:  Y Ito; H Komada; S Kusagawa; M Tsurudome; H Matsumura; M Kawano; H Ohta; M Nishio
Journal:  J Virol       Date:  1992-10       Impact factor: 5.103

9.  Fusion properties of cells infected with human parainfluenza virus type 3: receptor requirements for viral spread and virus-mediated membrane fusion.

Authors:  A Moscona; R W Peluso
Journal:  J Virol       Date:  1992-11       Impact factor: 5.103

10.  Replication of mumps virus in mouse: transient replication in lung and potential of systemic infection.

Authors:  M Tsurudome; A Yamada; M Hishiyama; Y Ito
Journal:  Arch Virol       Date:  1987       Impact factor: 2.574
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