Literature DB >> 3760157

Cortisol stimulation by recombinant interferon-alpha 2.

J Roosth, R B Pollard, S L Brown, W J Meyer.   

Abstract

Serum cortisol concentrations were determined by radioimmunoassay in cancer patients undergoing experimental therapy with recombinant interferon-alpha 2. Cortisol concentration rose steadily after interferon administration and was significantly different from that on control day at 8 h following intramuscular injection of interferon-alpha 2. Cortisol elevation was increased as weekly doses of interferon were increased (0-120 X 10(6) units). Recent clinical trials of interferons for treatment of neurological and malignant diseases provide a compelling need to understand the actions and side effects of exogenously administered interferons.

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Year:  1986        PMID： 3760157     DOI： 10.1016/0165-5728(86)90037-8

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  8 in total

Review 1.  Hormones and the immune response.

Authors:  A K Bhalla
Journal:  Ann Rheum Dis       Date:  1989-01       Impact factor: 19.103

2.  Effect of interferon-alpha on DOI-induced wet-dog shakes in rats.

Authors:  A Kugaya; A Kagaya; Y Uchitomi; N Yokota; S Yamawaki
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

3.  Effects of chronic administration of interferon alpha A/D on serotonergic receptors in rat brain.

Authors:  S Abe; T Hori; T Suzuki; A Baba; H Shiraishi; T Yamamoto
Journal:  Neurochem Res       Date:  1999-03       Impact factor: 3.996

4.  Effect of interferon alpha on high serum androgen concentrations in HIV positive men with Kaposi's sarcoma.

Authors:  N Christeff; S Gharakhanian; N Thobie; E Wirbel; M T Dalle; D Costagliola; E A Nunez; W Rozenbaum
Journal:  J Clin Pathol       Date:  1997-04       Impact factor: 3.411

Review 5.  Immune modulation of the hypothalamic-pituitary-adrenal (HPA) axis during viral infection.

Authors:  Marni N Silverman; Brad D Pearce; Christine A Biron; Andrew H Miller
Journal:  Viral Immunol       Date:  2005       Impact factor: 2.257

6.  Relation between leukocyte counts and cortisol secretion in CML patients undergoing combined TNF alpha/IFN alpha therapy.

Authors:  M Nagel-Hiemke; C Hiemke; G Kummer; T Moritz; H Müller; S Seeber; N Niederle
Journal:  Ann Hematol       Date:  1992-09       Impact factor: 3.673

7.  Suppression of thyroid function by interferon-alpha 2 in man.

Authors:  C J Wiedermann; W Vogel; H Tilg; F J Wiedermann; M Herold; U Zilian; T Wohlfarter; M Gruber; H Braunsteiner
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-06       Impact factor: 3.000

Review 8.  Interferons in multiple sclerosis. A review of the evidence.

Authors:  H S Panitch
Journal:  Drugs       Date:  1992-12       Impact factor: 9.546
  8 in total

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