Literature DB >> 3759655

Capuramycin, a new nucleoside antibiotic. Taxonomy, fermentation, isolation and characterization.

H Yamaguchi, S Sato, S Yoshida, K Takada, M Itoh, H Seto, N Otake.   

Abstract

A new antibiotic capuramycin was isolated from the culture filtrate of Streptomyces griseus 446-S3 by adsorption and partition column chromatography. Based on its chemical structure being an uracil nucleoside with a caprolactam substituent, this substance was named as capuramycin. This paper describes the taxonomy of a producing organism, fermentation, isolation, characterization and biological properties of capuramycin.

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Year:  1986        PMID： 3759655     DOI： 10.7164/antibiotics.39.1047

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  21 in total

1.  Chemical modification of capuramycins to enhance antibacterial activity.

Authors:  Elena Bogatcheva; Tia Dubuisson; Marina Protopopova; Leo Einck; Carol A Nacy; Venkata M Reddy
Journal:  J Antimicrob Chemother       Date:  2010-12-23       Impact factor: 5.790

2.  In vitro antimycobacterial activities of capuramycin analogues.

Authors:  Venkata M Reddy; Leo Einck; Carol A Nacy
Journal:  Antimicrob Agents Chemother       Date:  2007-12-10       Impact factor: 5.191

Review 3.  New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development.

Authors:  Masayuki Igarashi; Yoshimasa Ishizaki; Yoshiaki Takahashi
Journal:  J Antibiot (Tokyo)       Date:  2017-11-01       Impact factor: 2.649

Review 4.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

5.  Bioactive compounds from marine actinomycetes.

Authors:  Renu Solanki; Monisha Khanna; Rup Lal
Journal:  Indian J Microbiol       Date:  2009-01-08       Impact factor: 2.461

6.  Improved synthesis of capuramycin and its analogues.

Authors:  Yong Wang; Shajila Siricilla; Bilal A Aleiwi; Michio Kurosu
Journal:  Chemistry       Date:  2013-09-06       Impact factor: 5.236

7.  A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW.

Authors:  Xiaodong Liu; Yuanyuan Jin; Wenlong Cai; Keith D Green; Anwesha Goswami; Sylvie Garneau-Tsodikova; Koichi Nonaka; Satoshi Baba; Masanori Funabashi; Zhaoyong Yang; Steven G Van Lanen
Journal:  Org Biomol Chem       Date:  2016-04-06       Impact factor: 3.876

8.  The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

Authors:  Wenlong Cai; Anwesha Goswami; Zhaoyong Yang; Xiaodong Liu; Keith D Green; Sandra Barnard-Britson; Satoshi Baba; Masanori Funabashi; Koichi Nonaka; Manjula Sunkara; Andrew J Morris; Anatol P Spork; Christian Ducho; Sylvie Garneau-Tsodikova; Jon S Thorson; Steven G Van Lanen
Journal:  J Biol Chem       Date:  2015-04-08       Impact factor: 5.157

9.  DPAGT1 Inhibitors of Capuramycin Analogues and Their Antimigratory Activities of Solid Tumors.

Authors:  Katsuhiko Mitachi; Rita G Kansal; Kirk E Hevener; Cody D Gillman; Syed M Hussain; Hyun Gi Yun; Gustavo A Miranda-Carboni; Evan S Glazer; William M Clemons; Michio Kurosu
Journal:  J Med Chem       Date:  2020-09-18       Impact factor: 7.446

10.  Isolation and characterization of racemase from Ensifer sp. 23-3 that acts on α-aminolactams and α-amino acid amides.

Authors:  Daisuke Matsui; Ken-Ichi Fuhshuku; Shingo Nagamori; Momoko Takata; Yasuhisa Asano
Journal:  J Ind Microbiol Biotechnol       Date:  2017-09-19       Impact factor: 3.346
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