Literature DB >> 3759240

Ocular sensitization of mice by live (but not irradiated) Chlamydia trachomatis serovar A.

D G Colley, T G Goodman, I S Barsoum.   

Abstract

Ocular exposure of mice to live elementary bodies of Chlamydia trachomatis serovar A results in immunological sensitization of the mice. This reactivity is manifested by the development of early (5 h) and delayed-type (24 h) dermal reactivity and serovar-specific antibody formation against either live or irradiated (100 kilorads) elementary bodies. Parallel ocular exposure of mice to irradiated elementary bodies does not result in this sensitization. The early and late dermal immune responses induced by ocular exposure to live organisms can be transferred to unexposed mice by serum and lymphoid cell transfers, respectively. It appears that successful murine ocular sensitization by human C. trachomatis serovar A elementary bodies is an ability manifested by live organisms and not by inactivated but antigenic organisms.

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Year:  1986        PMID： 3759240      PMCID： PMC260108          DOI： 10.1128/iai.54.1.9-12.1986

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  16 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Pannus with experimental trachoma and inclusion conjunctivitis agent infection of Taiwan monkeys.

Authors:  S P Wang; J T Grayston
Journal:  Am J Ophthalmol       Date:  1967-05       Impact factor: 5.258

Review 3.  Detection of chlamydiae by isolation and direct examination.

Authors:  R T Evans; R M Woodland
Journal:  Br Med Bull       Date:  1983-04       Impact factor: 4.291

Review 4.  Chlamydial classification, development and structure.

Authors:  M E Ward
Journal:  Br Med Bull       Date:  1983-04       Impact factor: 4.291

Review 5.  Animal models of chlamydial infection.

Authors:  R M Woodland; A P Johnson; M Tuffrey
Journal:  Br Med Bull       Date:  1983-04       Impact factor: 4.291

6.  Immune response in mice infected in the genital tract with mouse pneumonitis agent (Chlamydia trachomatis biovar).

Authors:  A L Barron; R G Rank; E B Moses
Journal:  Infect Immun       Date:  1984-04       Impact factor: 3.441

7.  Serologic responses to Schistosoma japonicum: evaluation of total and parasite-specific immunoglobulins during the course of murine infection.

Authors:  J V Little; C E Carter; D G Colley
Journal:  J Parasitol       Date:  1982-08       Impact factor: 1.276

8.  An animal model of trachoma II. The importance of repeated reinfection.

Authors:  H R Taylor; S L Johnson; R A Prendergast; J Schachter; C R Dawson; A M Silverstein
Journal:  Invest Ophthalmol Vis Sci       Date:  1982-10       Impact factor: 4.799

9.  The distribution and effect of Chlamydia trachomatis in CBA mice inoculated genitally, intra-articularly or intravenously.

Authors:  M Tuffrey; P Falder; B Thomas; D Taylor-Robinson
Journal:  Med Microbiol Immunol       Date:  1984       Impact factor: 3.402

10.  In vitro neutralization of Chlamydia trachomatis with monoclonal antibody to an epitope on the major outer membrane protein.

Authors:  R Peeling; I W Maclean; R C Brunham
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441
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  2 in total

1.  Monoclonal antibody neutralization of unmanipulated Chlamydia trachomatis serovar A infection of human epithelioid cells (A-431).

Authors:  I S Barsoum; T A Goodman; L K Hardin; D G Colley
Journal:  Med Microbiol Immunol       Date:  1989       Impact factor: 3.402

2.  Immune responses of mice after conjunctival exposure to Chlamydia trachomatis serovar A.

Authors:  I S Barsoum; L K Hardin; D G Colley
Journal:  Med Microbiol Immunol       Date:  1988       Impact factor: 3.402
  2 in total

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