Literature DB >> 375808

Thrombocytopenia associated with sodium valproate treatment.

A N Neophytides, J G Nutt, J R Lodish.   

Abstract

The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.

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Year:  1979        PMID： 375808     DOI： 10.1002/ana.410050414

Source DB:  PubMed          Journal:  Ann Neurol        ISSN： 0364-5134            Impact factor:   10.422


  4 in total

1.  Sodium valproate and thrombocytopenia.

Authors:  L M Hoffman
Journal:  Can Med Assoc J       Date:  1982-02-15       Impact factor: 8.262

2.  A case of valproate intoxication with excessive brain edema.

Authors:  G Hintze; H H Klein; H Prange; H Kreuzer
Journal:  Klin Wochenschr       Date:  1987-05-04

Review 3.  Intraoperative defect in haemostasis in a child receiving valproic acid.

Authors:  J E Tetzlaff
Journal:  Can J Anaesth       Date:  1991-03       Impact factor: 5.063

Review 4.  [Perioperative coagulation diagnostics].

Authors:  C-E Dempfle
Journal:  Anaesthesist       Date:  2005-02       Impact factor: 1.041
  4 in total

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