Literature DB >> 3758071

The mouse myoglobin gene. Characterisation and sequence comparison with other mammalian myoglobin genes.

A Blanchetot, M Price, A J Jeffreys.   

Abstract

Seal myoglobin (Mb) exons 1 and 3 were used as probes to isolate the functional mouse Mb gene. This gene has a very low level of Mb expression in skeletal muscle. Although it is shorter, the mouse Mb gene displays the common organisation found in human and seal Mb genes. In addition, we have defined blocks of conserved sequences in the 5' flanking region by comparison with other mammalian Mb genes. Moreover, about 10(3) bases upstream of the cap site we identified a repetitive B1 element directly associated with two overlapping open reading frames, containing a putative polyadenylation signal. A polypyrimidine-rich region has also been located upstream from the gene.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3758071     DOI： 10.1111/j.1432-1033.1986.tb09909.x

Source DB:  PubMed          Journal:  Eur J Biochem        ISSN： 0014-2956


  12 in total

1.  Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression?

Authors:  Glen Kristiansen; Junmin Hu; Daniela Wichmann; Daniel P Stiehl; Michael Rose; Josefine Gerhardt; Annette Bohnert; Anette ten Haaf; Holger Moch; James Raleigh; Mahesh A Varia; Patrick Subarsky; Francesca M Scandurra; Erich Gnaiger; Eva Gleixner; Anne Bicker; Max Gassmann; Thomas Hankeln; Edgar Dahl; Thomas A Gorr
Journal:  J Biol Chem       Date:  2011-09-19       Impact factor: 5.157

Review 2.  Regulation of myoglobin expression.

Authors:  Shane B Kanatous; Pradeep P A Mammen
Journal:  J Exp Biol       Date:  2010-08-15       Impact factor: 3.312

3.  Folding of apominimyoglobin.

Authors:  G De Sanctis; F Ascoli; M Brunori
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-22       Impact factor: 11.205

4.  Variable expression of myoglobin among the hemoglobinless Antarctic icefishes.

Authors:  B D Sidell; M E Vayda; D J Small; T J Moylan; R L Londraville; M L Yuan; K J Rodnick; Z A Eppley; L Costello
Journal:  Proc Natl Acad Sci U S A       Date:  1997-04-01       Impact factor: 11.205

5.  Disruption of myoglobin in mice induces multiple compensatory mechanisms.

Authors:  A Gödecke; U Flögel; K Zanger; Z Ding; J Hirchenhain; U K Decking; J Schrader
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-31       Impact factor: 11.205

6.  Requirement of TCTG(G/C) Direct Repeats and Overlapping GATA Site for Maintaining the Cardiac-Specific Expression of Cardiac troponin T in Developing and Adult Mice.

Authors:  Shannon M Harlan; Rebecca S Reiter; Curt D Sigmund; Jenny Li-Chun Lin; Jim Jung-Ching Lin
Journal:  Anat Rec (Hoboken)       Date:  2008-12       Impact factor: 2.064

7.  The microsatellite found in the DNA sequence with the code name MMMYOGG1 (GenBank) does not correspond to the myogenin gene (Myog) but to myoglobin (Mb) and maps to mouse chromosome 15.

Authors:  B Drouet; D Simon-Chazottes
Journal:  Mamm Genome       Date:  1993       Impact factor: 2.957

8.  Gradients of transgene expression directed by the human myoglobin promoter in the developing mouse heart.

Authors:  W J Parsons; J A Richardson; K H Graves; R S Williams; R W Moreadith
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

9.  Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter.

Authors:  J Grayson; R S Williams; Y T Yu; R Bassel-Duby
Journal:  Mol Cell Biol       Date:  1995-04       Impact factor: 4.272

10.  A 40-kilodalton protein binds specifically to an upstream sequence element essential for muscle-specific transcription of the human myoglobin promoter.

Authors:  R Bassel-Duby; M D Hernandez; M A Gonzalez; J K Krueger; R S Williams
Journal:  Mol Cell Biol       Date:  1992-11       Impact factor: 4.272
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.