Literature DB >> 3757781

Lidocaine excretion in breast milk.

J A Zeisler, T D Gaarder, S A De Mesquita.   

Abstract

Nursing mothers are occasionally treated with intravenous lidocaine for ventricular dysrhythmias. There have been no reports on the excretion of lidocaine into breast milk. This case documents the excretion of lidocaine into breast milk in small amounts and shows the validity of the TDx methodology used in the whole-milk lidocaine assay. We observed breast-milk concentrations of lidocaine at 40 percent of the serum levels. Clinical practitioners should be aware the lidocaine is excreted into breast milk in small amounts and the mother could probably continue to safely breast-feed her child while on parenteral lidocaine. Any adverse reactions in the nursing infant would probably be limited to an idiosyncratic or allergic reaction.

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Year:  1986        PMID: 3757781     DOI: 10.1177/106002808602000913

Source DB:  PubMed          Journal:  Drug Intell Clin Pharm        ISSN: 0012-6578


  8 in total

Review 1.  [Anesthesia in the breast feeding period. Excretion of anesthetic agents and adjuvants into breast milk and potential pharmacological side-effects on the suckling infant].

Authors:  C Lang; G Geldner; H Wulf
Journal:  Anaesthesist       Date:  2003-10       Impact factor: 1.041

Review 2.  [Anesthesia and analgesia in the lactation period. Criteria for drug selection].

Authors:  C A Nassen; C Schaefer; J Wirbelauer; A Hönig; P Kranke
Journal:  Anaesthesist       Date:  2014-05       Impact factor: 1.041

Review 3.  Cluster Headache: Special Considerations for Treatment of Female Patients of Reproductive Age and Pediatric Patients.

Authors:  Juliana VanderPluym
Journal:  Curr Neurol Neurosci Rep       Date:  2016-01       Impact factor: 5.081

Review 4.  Drugs in human milk. Clinical pharmacokinetic considerations.

Authors:  H C Atkinson; E J Begg; B A Darlow
Journal:  Clin Pharmacokinet       Date:  1988-04       Impact factor: 6.447

Review 5.  Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part I).

Authors:  J B Besunder; M D Reed; J L Blumer
Journal:  Clin Pharmacokinet       Date:  1988-04       Impact factor: 6.447

6.  Lidocaine patches for postcesarean pain control in obese women: a pilot randomized controlled trial.

Authors:  Kathleen M Antony; Jacquelyn H Adams; Laura Jacques; Scott Hetzel; Richard J Chappell; Sarah E Gnadt; Amye J Tevaarwerk
Journal:  Am J Obstet Gynecol MFM       Date:  2020-11-26

7.  The Effect of Adding Lidocaine to Patient Controlled Analgesia with Morphine on Pain Intensity after Caesarean Section with Spinal Anesthesia: A Double-Blind, Randomized, Clinical Trial.

Authors:  Ali Habibi; Abbas Alipour; Afshin Gholipour Baradari; Abdolmajid Gholinataj; Mohammad Reza Habibi; Saloumeh Peivandi
Journal:  Open Access Maced J Med Sci       Date:  2019-06-26

8.  [Should maternal anesthesia delay breastfeeding? A systematic review of the literature].

Authors:  Morenna Ramos E Oliveira; Murillo Gonçalves Santos; Débora Alves Aude; Rodrigo Moreira E Lima; Norma Sueli Pinheiro Módolo; Lais Helena Navarro
Journal:  Braz J Anesthesiol       Date:  2019-01-14
  8 in total

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