| Literature DB >> 375755 |
A J Gelenberg, J C Doller-Wojcik, J H Growdon.
Abstract
Tardive dyskinesia is thought to reflect increased dopaminergic activity of the central nervous system. To compensate for this by increasing CNS cholinergic tone, the authors administered oral choline and its natural dietary source, lecithin, to 5 men with mild to severe tardive dyskinesia in a nonblind trial. Both choline and lecithin increased serum choline levels and improved abnormal movements in all patients. Lecithin had fewer adverse effects.Entities:
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Year: 1979 PMID： 375755 DOI： 10.1176/ajp.136.6.772
Source DB: PubMed Journal: Am J Psychiatry ISSN： 0002-953X Impact factor: 18.112