Literature DB >> 3757480

Influence of age, sex, lactational state and exogenous growth hormone on erythrocyte UMP synthase in dairy cattle.

L R Jones, K K Harden, D S Bragg, J L Robinson.   

Abstract

UMP synthase activity was determined in erythrocytes of Holstein cattle to assess differences attributable to age, sex, lactational state, and exogenous growth hormone. Newborns had 80% more UMP synthase activity per ml erythrocytes than mature cattle. Males had 10% more UMP synthase activity than females of the same age. Lactating and non-lactating mature females did not differ in UMP synthase activity. Over the first six weeks of life, the decrease in UMP synthase activity was less pronounced in calves partially deficient for the enzyme. Ten daily injections of growth hormone altered neither UMP synthase activity in erythrocytes nor orotic acid concentrations in milk and urine.

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Year:  1986        PMID: 3757480     DOI: 10.1016/0305-0491(86)90112-4

Source DB:  PubMed          Journal:  Comp Biochem Physiol B        ISSN: 0305-0491


  4 in total

1.  Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families.

Authors:  M Suchi; H Mizuno; Y Kawai; T Tsuboi; S Sumi; K Okajima; M E Hodgson; H Ogawa; Y Wada
Journal:  Am J Hum Genet       Date:  1997-03       Impact factor: 11.025

2.  Deficiency of UMP synthase in dairy cattle: a model for hereditary orotic aciduria.

Authors:  K K Harden; J L Robinson
Journal:  J Inherit Metab Dis       Date:  1987       Impact factor: 4.982

3.  Characterization of UMP synthase in dairy cattle heterozygous for a lethal recessive trait.

Authors:  K K Harden; J L Robinson
Journal:  Biochem Genet       Date:  1987-08       Impact factor: 1.890

4.  Meiotic nondisjunction and recombination of chromosome III and homologous fragments in Saccharomyces cerevisiae.

Authors:  M Goldway; T Arbel; G Simchen
Journal:  Genetics       Date:  1993-02       Impact factor: 4.562

  4 in total

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