Literature DB >> 3756942

High-dose alpha-tocopherol as a preventive of doxorubicin-induced alopecia.

J E Perez, M Macchiavelli, B A Leone, A Romero, M G Rabinovich, D Goldar, C Vallejo.   

Abstract

The effectiveness of alpha-tocopherol acetate as a preventive of doxorubicin-induced alopecia was evaluated in 20 patients with different types of solid tumors. All received therapy containing doxorubicin in a dose range of 50-60 mg/m2/cycle of treatment. The observed hair loss was severe in 90% and moderate in 10% of the patients. No protective activity of alpha-tocopherol was demonstrated in this trial.

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Year:  1986        PMID: 3756942

Source DB:  PubMed          Journal:  Cancer Treat Rep        ISSN: 0361-5960


  3 in total

1.  Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia.

Authors:  Hisayoshi Imanishi; Daisuke Tsuruta; Chiharu Tateishi; Koji Sugawara; Ralf Paus; Tsutomu Tsuji; Masamitsu Ishii; Kazuo Ikeda; Hiroyuki Kunimoto; Koichi Nakajima; Jonathan C R Jones; Hiromi Kobayashi
Journal:  J Dermatol Sci       Date:  2010-02-16       Impact factor: 4.563

2.  Doxorubicin-induced hair loss in the Angora rabbit: a study of treatments to protect against the hair loss.

Authors:  G Powis; K L Kooistra
Journal:  Cancer Chemother Pharmacol       Date:  1987       Impact factor: 3.333

Review 3.  Prevention and Treatment of Chemotherapy-Induced Alopecia.

Authors:  Alfredo Rossi; Gemma Caro; Maria Caterina Fortuna; Flavia Pigliacelli; Andrea D'Arino; Marta Carlesimo
Journal:  Dermatol Pract Concept       Date:  2020-06-29
  3 in total

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