Literature DB >> 375559

Spina bifida in the dog.

J W Wilson, H J Kurtz, H W Leipold, G E Lees.   

Abstract

Spina bifida was diagnosed in four English Bulldogs and one Collie dog. These cases and the examination of records from the Veterinary Medical Data Program suggested a high incidence of spina bifida in the English Bulldog. Urinary and fecal incontinence was the most common reason for initial examination for the five dogs. Radiographs and myelography confirmed the diagnosis of spina bifida. Blood, cerebrospinal fluid and urine analyses did not aid diagnosis but urocystitis was identified. In addition to spina bifida, clinical signs and morphologic changes in the spinal cords of all five dogs fulfilled the criteria for an additional diagnosis of spinal dysraphism. A common pathogenesis for the two conditions is suggested.

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Year:  1979        PMID: 375559     DOI: 10.1177/030098587901600202

Source DB:  PubMed          Journal:  Vet Pathol        ISSN: 0300-9858            Impact factor:   2.221


  3 in total

1.  Limited dorsal myeloschisis in three cats: a distinctive form of neural tube defect.

Authors:  Sarah Butterfield; Beatriz Garcia-Gonzalez; Colin J Driver; Clare Rusbridge
Journal:  JFMS Open Rep       Date:  2020-06-29

2.  Myelomeningocoele and a dermoid sinus-like lesion in a French bulldog.

Authors:  Stéphane Ployart; Ivan Doran; Eric Bomassi; Christophe Bille; Stéphane Libermann
Journal:  Can Vet J       Date:  2013-12       Impact factor: 1.008

3.  Genome-wide association mapping in dogs enables identification of the homeobox gene, NKX2-8, as a genetic component of neural tube defects in humans.

Authors:  Noa Safra; Alexander G Bassuk; Polly J Ferguson; Miriam Aguilar; Rochelle L Coulson; Nicholas Thomas; Peta L Hitchens; Peter J Dickinson; Karen M Vernau; Zena T Wolf; Danika L Bannasch
Journal:  PLoS Genet       Date:  2013-07-18       Impact factor: 5.917

  3 in total

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