Literature DB >> 3754016

Monoclonal antibodies against the fusion protein are protective in necrotizing mumps meningoencephalitis.

A Löve, R Rydbeck, G Utter, C Orvell, K Kristensson, E Norrby.   

Abstract

A monoclonal antibody against the fusion (F) protein of mumps virus was found to confer marked protection in mumps virus-induced encephalitis. Almost total prevention of extensive brain necrosis was found. This study indicates that the virus F protein is directly involved in the pathogenesis of brain necrosis.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3754016      PMCID： PMC252897     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

1.  Evaluation of survival in challenge experiments.

Authors:  F D Liddell
Journal:  Microbiol Rev       Date:  1978-03

2.  Protective effects of glycoprotein-specific monoclonal antibodies on the course of experimental mumps virus meningoencephalitis.

Authors:  J S Wolinsky; M N Waxham; A C Server
Journal:  J Virol       Date:  1985-03       Impact factor: 5.103

3.  The effects of monoclonal antibodies on biologic activities of structural proteins of Sendai virus.

Authors:  C Orvell; M Grandien
Journal:  J Immunol       Date:  1982-12       Impact factor: 5.422

4.  On the fragmentation of monoclonal IgG1, IgG2a, and IgG2b from BALB/c mice.

Authors:  P Parham
Journal:  J Immunol       Date:  1983-12       Impact factor: 5.422

5.  Non-neutralizing monoclonal antibodies can prevent lethal alphavirus encephalitis.

Authors:  A L Schmaljohn; E D Johnson; J M Dalrymple; G A Cole
Journal:  Nature       Date:  1982-05-06       Impact factor: 49.962

6.  Virulence and persistence of three prototype strains of mumps virus in newborn hamsters.

Authors:  J S Wolinsky; W G Stroop
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

Review 7.  The role of viral glycoproteins in adsorption, penetration, and pathogenicity of viruses.

Authors:  P W Choppin; A Scheid
Journal:  Rev Infect Dis       Date:  1980 Jan-Feb

8.  Comparative studies of five strains of mumps virus in vitro and in neonatal hamsters: evaluation of growth, cytopathogenicity, and neurovirulence.

Authors:  M McCarthy; B Jubelt; D B Fay; R T Johnson
Journal:  J Med Virol       Date:  1980       Impact factor: 2.327

9.  Induction of subacute murine measles encephalitis by monoclonal antibody to virus haemagglutinin.

Authors:  K W Rammohan; H F McFarland; D E McFarlin
Journal:  Nature       Date:  1981-04-16       Impact factor: 49.962

10.  Hydrocephalus following viral infection: the pathology of aqueductal stenosis developing after experimental mumps virus infection.

Authors:  R T Johnson; K P Johnson
Journal:  J Neuropathol Exp Neurol       Date:  1968-10       Impact factor: 3.685
View more
  11 in total

1.  Amelioration of established Sendai viral pneumonia in the nude mouse using a monoclonal antibody to the virus fusion protein.

Authors:  P Carthew; J Riley; D Dinsdale
Journal:  Br J Exp Pathol       Date:  1989-12

2.  Protective effect of serum antibody on respiratory infection of influenza C virus in rats.

Authors:  K Takiguchi; K Sugawara; S Hongo; H Nishimura; F Kitame; K Nakamura
Journal:  Arch Virol       Date:  1992       Impact factor: 2.574

3.  Antibody protects against lethal infection with the neurally spreading reovirus type 3 (Dearing).

Authors:  H W Virgin; R Bassel-Duby; B N Fields; K L Tyler
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

Review 4.  Mumps: an Update on Outbreaks, Vaccine Efficacy, and Genomic Diversity.

Authors:  Eugene Lam; Jennifer B Rosen; Jane R Zucker
Journal:  Clin Microbiol Rev       Date:  2020-02-26       Impact factor: 26.132

5.  Protection against lethal measles virus infection in mice by immune-stimulating complexes containing the hemagglutinin or fusion protein.

Authors:  T M Varsanyi; B Morein; A Löve; E Norrby
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

6.  Correlation between humoral immune responses and presence of virus in the CNS in dogs experimentally infected with canine distemper virus.

Authors:  B K Rima; N Duffy; W J Mitchell; B A Summers; M J Appel
Journal:  Arch Virol       Date:  1991       Impact factor: 2.574

7.  A vaccinia virus double recombinant expressing the F and H genes of rinderpest virus protects cattle against rinderpest and causes no pock lesions.

Authors:  L Giavedoni; L Jones; C Mebus; T Yilma
Journal:  Proc Natl Acad Sci U S A       Date:  1991-09-15       Impact factor: 11.205

8.  Clearance of a persistent paramyxovirus infection is mediated by cellular immune responses but not by serum-neutralizing antibody.

Authors:  D F Young; R E Randall; J A Hoyle; B E Souberbielle
Journal:  J Virol       Date:  1990-11       Impact factor: 5.103

9.  Protective effect of antibodies to two viral envelope glycoproteins on lethal infection with Newcastle disease virus.

Authors:  Y Umino; T Kohama; M Kohase; A Sugiura; H D Klenk; R Rott
Journal:  Arch Virol       Date:  1987       Impact factor: 2.574

10.  Antibody inhibits defined stages in the pathogenesis of reovirus serotype 3 infection of the central nervous system.

Authors:  K L Tyler; H W Virgin; R Bassel-Duby; B N Fields
Journal:  J Exp Med       Date:  1989-09-01       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.