Literature DB >> 3753746

Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit.

J Boulter, K Evans, D Goldman, G Martin, D Treco, S Heinemann, J Patrick.   

Abstract

We have isolated a complementary DNA clone containing sequences homologous to those encoding the alpha-subunit of a mouse muscle nicotinic acetylcholine receptor. Based on the structural similarities between the encoded protein and the muscle acetylcholine receptor alpha-subunit, and the presence of hybridizing RNA species in the brain, we propose that this clone codes for a neural nicotinic acetylcholine receptor alpha-subunit.

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Year:  1986        PMID: 3753746     DOI: 10.1038/319368a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  84 in total

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