Literature DB >> 3753537

Urinary neopterin reflects clinical activity in patients with rheumatoid arthritis.

G Reibnegger, D Egg, D Fuchs, R Günther, A Hausen, E R Werner, H Wachter.   

Abstract

Neopterin is a marker for activation of cellular immunity. Urinary neopterin levels were measured in 106 patients with rheumatoid arthritis (RA) and in 45 patients with osteoarthritis. Levels were significantly higher in RA patients than in osteoarthritis patients and were strongly dependent on stage and activity of RA. Correlations with other laboratory parameters were weak. Multivariate analysis demonstrated that urinary neopterin levels reflected clinical activity better than did other laboratory findings. Thus, urinary neopterin determination might be useful in monitoring RA patients.

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Year:  1986        PMID: 3753537     DOI: 10.1002/art.1780290902

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  20 in total

1.  Macrophage activation and coronary atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis.

Authors:  Young Hee Rho; Joseph Solus; Paolo Raggi; Annette Oeser; Tebeb Gebretsadik; Ayumi Shintani; C Michael Stein
Journal:  Arthritis Care Res (Hoboken)       Date:  2011-04       Impact factor: 4.794

2.  Correlation between synovial neopterin and inflammatory activity in rheumatoid arthritis.

Authors:  A Krause; H Protz; K M Goebel
Journal:  Ann Rheum Dis       Date:  1989-08       Impact factor: 19.103

Review 3.  Neopterin as a biomarker of immune response in cancer patients.

Authors:  Bohuslav Melichar; Martina Spisarová; Marie Bartoušková; Lenka Kujovská Krčmová; Lenka Javorská; Hana Študentová
Journal:  Ann Transl Med       Date:  2017-07

4.  Neopterin excretion does not correlate with erythrocyte sedimentation rate.

Authors:  A Hausen; D Fuchs; G Reibnegger; E R Werner; H Wachter
Journal:  Klin Wochenschr       Date:  1987-12-15

Review 5.  Interaction of inflammatory cytokines and erythropoeitin in iron metabolism and erythropoiesis in anaemia of chronic disease.

Authors:  M Jongen-Lavrencic; H R Peeters; G Vreugdenhil; A J Swaak
Journal:  Clin Rheumatol       Date:  1995-09       Impact factor: 2.980

6.  Urinary neopterin in idiopathic retinal vasculitis.

Authors:  H E Palmer; G Giovannoni; M R Stanford; G R Wallace; E M Graham
Journal:  Br J Ophthalmol       Date:  2001-01       Impact factor: 4.638

7.  Serum neopterin levels in children with hepatitis-B-related chronic liver disease and its relationship to disease severity.

Authors:  Enver Mahir Gulcan; Ipek Tirit; Ayse Anil; Erdal Adal; Gulsen Ozbay
Journal:  World J Gastroenterol       Date:  2008-11-28       Impact factor: 5.742

8.  Modulation of monocyte activation in patients with rheumatoid arthritis by leukapheresis therapy.

Authors:  G Hahn; B Stuhlmüller; N Hain; J R Kalden; K Pfizenmaier; G R Burmester
Journal:  J Clin Invest       Date:  1993-03       Impact factor: 14.808

9.  Disease severity in rheumatoid arthritis: relationships of plasma tumor necrosis factor-alpha, soluble interleukin 2-receptor, soluble CD4/CD8 ratio, neopterin, and fibrin D-dimer to traditional severity and functional measures.

Authors:  J C Beckham; D S Caldwell; B L Peterson; A M Pippen; M S Currie; F J Keefe; J B Weinberg
Journal:  J Clin Immunol       Date:  1992-09       Impact factor: 8.317

Review 10.  Potential to inhibit growth of atherosclerotic plaque development through modulation of macrophage neopterin/7,8-dihydroneopterin synthesis.

Authors:  S P Gieseg; E M Crone; E A Flavall; Z Amit
Journal:  Br J Pharmacol       Date:  2007-08-13       Impact factor: 8.739

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