Literature DB >> 3753504

Elevation of blood lipid peroxide (TBA-reacting substance) level in developing chick embryos after glucocorticoid administration.

H Nishigori, J W Lee, Y Yamauchi, M Iwatsuru.   

Abstract

When 15-day-old chick embryos were administered 0.25 mumol of hydrocortisone hemisuccinate sodium (HC) the lipid peroxides (LPO) level increased after a lag time and reached about 9-fold of control level at 48 h after the treatment. Thereafter, the amount of LPO decreased to near control level by 72 h. Data obtained by using various steroids indicated that the marked elevation of LPO in blood was related to glucocorticoid effects caused by a high dose administration. The elevation of LPO level in blood was prevented by triple administration of ascorbic acid (20 mumol/egg) at 3, 10 and 20 h after HC treatment.

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Year:  1986        PMID： 3753504

Source DB:  PubMed          Journal:  Biochem Int        ISSN： 0158-5231


  3 in total

1.  Dexamethasone induced alterations in enzymatic and nonenzymatic antioxidant status in heart and kidney of rats.

Authors:  S Rajashree; R Puvanakrishnan
Journal:  Mol Cell Biochem       Date:  1998-04       Impact factor: 3.396

2.  Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.

Authors:  Wiebke Albrecht; Franziska Kappenberg; Tim Brecklinghaus; Iain Gardner; Jörg Rahnenführer; Jan G Hengstler; Regina Stoeber; Rosemarie Marchan; Mian Zhang; Kristina Ebbert; Hendrik Kirschner; Marianna Grinberg; Marcel Leist; Wolfgang Moritz; Cristina Cadenas; Ahmed Ghallab; Jörg Reinders; Nachiket Vartak; Christoph van Thriel; Klaus Golka; Laia Tolosa; José V Castell; Georg Damm; Daniel Seehofer; Alfonso Lampen; Albert Braeuning; Thorsten Buhrke; Anne-Cathrin Behr; Axel Oberemm; Xiaolong Gu; Naim Kittana; Bob van de Water; Reinhard Kreiling; Susann Fayyaz; Leon van Aerts; Bård Smedsrød; Heidrun Ellinger-Ziegelbauer; Thomas Steger-Hartmann; Ursula Gundert-Remy; Anja Zeigerer; Anett Ullrich; Dieter Runge; Serene M L Lee; Tobias S Schiergens; Lars Kuepfer; Alejandro Aguayo-Orozco; Agapios Sachinidis; Karolina Edlund
Journal:  Arch Toxicol       Date:  2019-06-27       Impact factor: 5.153

3.  Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models.

Authors:  Justin Komguep Nono; Kai Fu; Thabo Mpotje; Georgianna Varrone; Nada Abdel Aziz; Paballo Mosala; Lerato Hlaka; Severin Donald Kamdem; Daigen Xu; Thomas Spangenberg; Frank Brombacher
Journal:  Sci Rep       Date:  2020-06-30       Impact factor: 4.379
  3 in total

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