Literature DB >> 3752979

Comparative in vitro evaluation of cefonicid, cefazolin, and penicillin against viridans group streptococci isolated from blood.

M P Weinstein.   

Abstract

The in vitro activity of cefonicid against 60 strains of viridans group streptococci isolated from blood of patients with bacteremia and infective endocarditis was compared with those of cefazolin and penicillin. Cefonicid was less active than cefazolin, and both cephalosporins were less active than penicillin. The MIC50 and MIC90 for the strains tested were 0.06 and 1 microgram/ml for penicillin, 0.125 and 8 micrograms/ml for cefazolin, and 4 and 32 micrograms/ml for cefonicid.

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Year:  1986        PMID： 3752979      PMCID： PMC176464          DOI： 10.1128/AAC.30.1.187

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Treatment of penicillin-sensitive streptococcal infective endocarditis.

Authors:  W R Wilson; E R Giuliani; J E Geraci
Journal:  Mayo Clin Proc       Date:  1982-02       Impact factor: 7.616

2.  Speciation of the "viridans" streptococci.

Authors:  M Sands; H M Sommers; M B Rubin
Journal:  Am J Clin Pathol       Date:  1982-07       Impact factor: 2.493

3.  Antimicrobial susceptibilities of species of viridans streptococci.

Authors:  A M Bourgault; W R Wilson; J A Washington
Journal:  J Infect Dis       Date:  1979-09       Impact factor: 5.226

4.  SK&F 75073, new parenteral broad-spectrum cephalosporin with high and prolonged serum levels.

Authors:  P Actor; J V Uri; I Zajac; J R Guarini; L Phillips; D H Pitkin; D A Berges; G L Dunn; J R Hoover; J A Weisbach
Journal:  Antimicrob Agents Chemother       Date:  1978-05       Impact factor: 5.191

5.  The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. I. Laboratory and epidemiologic observations.

Authors:  M P Weinstein; L B Reller; J R Murphy; K A Lichtenstein
Journal:  Rev Infect Dis       Date:  1983 Jan-Feb

6.  Evaluation of the cefonicid disk test criteria, including disk quality control guidelines.

Authors:  A L Barry; R N Jones; C Thornsberry
Journal:  J Clin Microbiol       Date:  1983-02       Impact factor: 5.948

7.  In vitro experience with cefonicid.

Authors:  P Actor
Journal:  Rev Infect Dis       Date:  1984 Nov-Dec

8.  Failure of a once-daily regimen of cefonicid for treatment of endocarditis due to Staphylococcus aureus.

Authors:  H F Chambers; J Mills; T A Drake; M A Sande
Journal:  Rev Infect Dis       Date:  1984 Nov-Dec

9.  Evaluation of the Rapid Strep system for the identification of clinical isolates of Streptococcus species.

Authors:  R R Facklam; D L Rhoden; P B Smith
Journal:  J Clin Microbiol       Date:  1984-11       Impact factor: 5.948
  9 in total

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