Effect of phloridzin on lipid biosynthesis by Cladosporium tenuissimum Cooke.

A local strains of Cladosporium tenuissimum was found unsuitable as a producer of lipid. Addition of phloridzin to the fermentation media induced this organism to accumulate a moderate level of lipid, especially sterols increased highly in the presence of phloridzin. The promoting effect of phloridzin may be due to directing the sugar breakdown towards lipid biosynthesis and/or transforming the free fatty acids and oxalacetic acid to acetyl-Co A.