Literature DB >> 3748887

Diazepam inhibits proliferation of the mouse spleen lymphocytes in vitro.

M Pawlikowski, H Stepień, J Kunert-Radek.   

Abstract

The effects of diazepam (1-100 microM) on the incorporation of 3H-thymidine into DNA of the mouse spleen lymphocytes in vitro have been investigated. A dose-dependent inhibition of lymphocyte DNA synthesis has been found. A 70% inhibition occurred with 100 microM diazepam concentration.

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Year:  1986        PMID： 3748887

Source DB:  PubMed          Journal:  Pol J Pharmacol Pharm        ISSN： 0301-0244


  3 in total

1.  Effect of benzodiazepines on the proliferation of mouse spleen lymphocytes in vitro.

Authors:  M Pawlikowski; K Lysoń; J Kunert-Radek; H Stepień
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575

2.  Enhancement of estradiol-induced DNA synthesis in the anterior pituitary gland by the peripheral-type benzodiazepine receptor ligand Ro 5-4864.

Authors:  H Stepień; J Kunert-Radek; M Pawlikowski
Journal:  J Neural Transm       Date:  1986       Impact factor: 3.575

3.  Melatonin and vitamin C administration ameliorate diazepam-induced oxidative stress and cell proliferation in the liver of rats.

Authors:  G H El-Sokkary
Journal:  Cell Prolif       Date:  2008-02       Impact factor: 6.831
  3 in total

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