Literature DB >> 374761

Combined amphotericin B-flucytosine therapy in Aspergillus pneumonia.

S D Codish, J S Tobias, M Hannigan.   

Abstract

The incidence of aspergillosis is increasing while the prognosis remains dismal. Standard single-drug therapy with amphotericin B offers unacceptably low cure rates. A patient with Aspergillus pneumonia was treated with a synergistic combination of amphotericin B and flucytosine. A prompt clinical response and progressive resolution of the infection were observed. Combination therapy appeared to decrease the dose of amphotericin B needed for effective therapy. It may provide improved results with decreased toxic effects.

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Year:  1979        PMID： 374761

Source DB:  PubMed          Journal:  JAMA        ISSN： 0098-7484            Impact factor:   56.272


  12 in total

Review 1.  Intracerebral Aspergillus abscess: case report and review of the literature.

Authors:  M Artico; F S Pastore; M Polosa; S Sherkat; M Neroni
Journal:  Neurosurg Rev       Date:  1997       Impact factor: 3.042

2.  Combination antifungal therapy for the treatment of invasive yeast and mold infections.

Authors:  John W Baddley; Peter G Pappas
Journal:  Curr Infect Dis Rep       Date:  2007-11       Impact factor: 3.725

Review 3.  In vitro and in vivo evaluation of antifungal agents.

Authors:  A Espinel-Ingroff; S Shadomy
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-04       Impact factor: 3.267

4.  Invasive pulmonary aspergillosis in a non-immunosuppressed patient: successful management with systemic amphotericin and flucytosine and inhaled amphotericin.

Authors:  S Rodenhuis; F Beaumont; H F Kauffman; H J Sluiter
Journal:  Thorax       Date:  1984-01       Impact factor: 9.139

5.  Successful treatment of invasive pulmonary aspergillosis complicating influenza A.

Authors:  D T McLeod; L J Milne; A Seaton
Journal:  Br Med J (Clin Res Ed)       Date:  1982-10-23

6.  Pneumonia during the treatment of acute leukaemia.

Authors: 
Journal:  Br Med J       Date:  1980-11-08

7.  Successful treatment of invasive pulmonary aspergillosis in a patient with acute leukaemia.

Authors:  B D Daly; A Doherty; S R McCann
Journal:  Ir J Med Sci       Date:  1983-02       Impact factor: 1.568

Review 8.  Cryptogenic organizing pneumonia associated with invasive pulmonary aspergillosis: a case report and review of the literature.

Authors:  Shuanshuan Xie; Changxing Shen; Yunfeng Zhang; Kun Lu; Feng Hu; Min Tan; Haiyan Lin; Lei Xu; Qing Yuan; Xiaolian Song; Changhui Wang
Journal:  Int J Clin Exp Pathol       Date:  2014-12-01

9.  In vitro activities of amphotericin B in combination with four antifungal agents and rifampin against Aspergillus spp.

Authors:  C E Hughes; C Harris; J A Moody; L R Peterson; D N Gerding
Journal:  Antimicrob Agents Chemother       Date:  1984-05       Impact factor: 5.191

Review 10.  Aspergillosis of the CNS in a pediatric liver transplant recipient: case report and review.

Authors:  M Green; E R Wald; A Tzakis; S Todo; T E Starzl
Journal:  Rev Infect Dis       Date:  1991 Jul-Aug
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