| Literature DB >> 374687 |
R S Walls, D V Philcox, C L Cullis.
Abstract
Sensitisation to brain antigen was demonstrated in eight of 24 clinically normal first generation children in a family with hereditary ataxia. This ratio is consistent with that expected in a dominantly inherited condition. It suggests that immunological reactivity may precede the clinical expression of disease, with important implications for presymptomatic diagnosis and for pathogenesis of degenerative disease.Entities:
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Year: 1979 PMID： 374687 PMCID： PMC490721 DOI： 10.1136/jnnp.42.3.203
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154