Literature DB >> 3746349

The immunocytochemical demonstration of copper-zinc superoxide dismutase in the brain.

L G Thaete, R K Crouch, F Nakagawa, S S Spicer.   

Abstract

Copper-zinc superoxide dismutase (CuZn-SOD) has been localized in formalin-fixed, paraffin-embedded sections of both canine and rat brains. Staining with an immunoenzyme bridge sequence revealed CuZn-SOD in all regions of the brains examined. Specific sites of localization included cerebral cortical pyramidal cells, cerebellar Purkinje cells, neurons in 'subcortical nuclei', and oligodendrocytes throughout the brain. Similar sites of CuZn-SOD localization were identified in both species. These results are compared with reports by various investigators of SOD bioactivity in the brain.

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Year:  1986        PMID： 3746349     DOI： 10.1007/bf01611436

Source DB:  PubMed          Journal:  J Neurocytol        ISSN： 0300-4864


  3 in total

1.  Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.

Authors:  C A Pardo; Z Xu; D R Borchelt; D L Price; S S Sisodia; D W Cleveland
Journal:  Proc Natl Acad Sci U S A       Date:  1995-02-14       Impact factor: 11.205

2.  Cu/Zn superoxide dismutase expression in the postnatal rat brain following an excitotoxic injury.

Authors:  Hugo Peluffo; Laia Acarin; Maryam Faiz; Bernardo Castellano; Berta Gonzalez
Journal:  J Neuroinflammation       Date:  2005-06-01       Impact factor: 8.322

3.  SOD1 Lysine 123 Acetylation in the Adult Central Nervous System.

Authors:  Michael Kaliszewski; Austin K Kennedy; Shelby L Blaes; Robert S Shaffer; Andrew B Knott; Wenjun Song; Henry A Hauser; Blaise Bossy; Ting-Ting Huang; Ella Bossy-Wetzel
Journal:  Front Cell Neurosci       Date:  2016-12-20       Impact factor: 5.505
  3 in total

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