Literature DB >> 3746295

Ferritin as an iron-storage protein: mechanisms of iron uptake.

P M Harrison, A Treffry, T H Lilley.   

Abstract

The major physiological role of the ubiquitous protein ferritin is to store iron, which it does as a mineral core within a protein shell. Using evidence from a variety of sources we suggest that this versatile protein responds in its mechanism of iron uptake to changes in environmental conditions.

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Year:  1986        PMID： 3746295     DOI： 10.1016/0162-0134(86)80068-x

Source DB:  PubMed          Journal:  J Inorg Biochem        ISSN： 0162-0134            Impact factor:   4.155


  5 in total

1.  Molecular diffusion into ferritin: pathways, temperature dependence, incubation time, and concentration effects.

Authors:  X Yang; P Arosio; N D Chasteen
Journal:  Biophys J       Date:  2000-04       Impact factor: 4.033

2.  Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin.

Authors:  E M Coccia; V Profita; G Fiorucci; G Romeo; E Affabris; U Testa; M W Hentze; A Battistini
Journal:  Mol Cell Biol       Date:  1992-07       Impact factor: 4.272

3.  Iron uptake in ferritin is blocked by binding of [Cr(TREN)(H(2)O)(OH)](2+), a slow dissociating model for [Fe(H(2)O)(6)](2+).

Authors:  Carmen M Barnés; Elizabeth C Theil; Kenneth N Raymond
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-16       Impact factor: 11.205

4.  Defining the roles of the threefold channels in iron uptake, iron oxidation and iron-core formation in ferritin: a study aided by site-directed mutagenesis.

Authors:  A Treffry; E R Bauminger; D Hechel; N W Hodson; I Nowik; S J Yewdall; P M Harrison
Journal:  Biochem J       Date:  1993-12-15       Impact factor: 3.857

5.  Evidence of H- and L-chains have co-operative roles in the iron-uptake mechanism of human ferritin.

Authors:  S Levi; S J Yewdall; P M Harrison; P Santambrogio; A Cozzi; E Rovida; A Albertini; P Arosio
Journal:  Biochem J       Date:  1992-12-01       Impact factor: 3.857
  5 in total

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