Literature DB >> 3741770

Dose-dependent localisation and potential for therapy of F(ab')2 fragments against CEA studied in a human tumour xenograft model.

G T Rogers, P J Harwood, R B Pedley, J Boden, K D Bagshawe.   

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Year:  1986        PMID： 3741770      PMCID： PMC2001517          DOI： 10.1038/bjc.1986.183

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


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  11 in total

Review 1.  Recent advances in tumour imaging. Use of radiolabelled antitumour antibodies.

Authors:  R H Begent
Journal:  Biochim Biophys Acta       Date:  1985

2.  Dose dependent localisation of a monoclonal F(ab')2 fragment against CEA in the mouse xenograft model.

Authors:  G T Rogers; J Boden; P J Harwood; R B Pedley; G A Rawlins; K D Bagshawe
Journal:  Eur J Cancer Clin Oncol       Date:  1986-06

3.  Preparation of F(ab')2 fragments from mouse IgG of various subclasses.

Authors:  E Lamoyi; A Nisonoff
Journal:  J Immunol Methods       Date:  1983-01-28       Impact factor: 2.303

Review 4.  Radioimmunodetection and radioimmunotherapy.

Authors:  S M Larson; J A Carrasquillo; J C Reynolds
Journal:  Cancer Invest       Date:  1984       Impact factor: 2.176

5.  Comparative tumour localization of antibody fragments and intact IgG in nude mice bearing a CEA-producing human colon tumour xenograft.

Authors:  P J Harwood; J Boden; R B Pedley; G Rawlins; G T Rogers; K D Bagshawe
Journal:  Eur J Cancer Clin Oncol       Date:  1985-12

6.  Localization of mammary tumors in vivo with 131I-labeled Fab fragments of antibodies against mouse mammary epithelial (MME) antigens.

Authors:  T Wilbanks; J A Peterson; S Miller; L Kaufman; D Ortendahl; R L Ceriani
Journal:  Cancer       Date:  1981-10-15       Impact factor: 6.860

7.  Improved radioimaging and tumor localization with monoclonal F(ab')2.

Authors:  R L Wahl; C W Parker; G W Philpott
Journal:  J Nucl Med       Date:  1983-04       Impact factor: 10.057

8.  Dynamics of monoclonal antibody distribution and prolonged tumour localisation in nude mice bearing a human CEA-producing colon carcinoma xenograft.

Authors:  G T Rogers; P J Harwood; R B Pedley; J Boden; G Rawlins; K D Bagshawe
Journal:  Tumour Biol       Date:  1986

9.  Tumor localization of radiolabeled antibodies against carcinoembryonic antigen in patients with carcinoma: a critical evaluation.

Authors:  J P Mach; S Carrel; M Forni; J Ritschard; A Donath; P Alberto
Journal:  N Engl J Med       Date:  1980-07-03       Impact factor: 91.245

10.  Radiolabeled fragments of monoclonal antibodies against carcinoembryonic antigen for localization of human colon carcinoma grafted into nude mice.

Authors:  F Buchegger; C M Haskell; M Schreyer; B R Scazziga; S Randin; S Carrel; J P Mach
Journal:  J Exp Med       Date:  1983-08-01       Impact factor: 14.307
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  6 in total

1.  Theoretical considerations for improving tumour targeting.

Authors:  G D Thomas; M J Chappell; P W Dykes; D B Ramsden; K R Godfrey; J R Ellis; A R Bradwell
Journal:  Br J Cancer Suppl       Date:  1990-07

Review 2.  Antibody-directed enzyme prodrug therapy.

Authors:  K D Bagshawe
Journal:  Clin Pharmacokinet       Date:  1994-11       Impact factor: 6.447

3.  Influence of antibody protein dose on therapeutic efficacy of radioiodinated antibodies in nude mice bearing GW-39 human tumor.

Authors:  O C Boerman; R M Sharkey; G Y Wong; R D Blumenthal; R L Aninipot; D M Goldenberg
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

4.  Effect of dose escalation of a monoclonal anti-CEA IgG on tumour localisation and tissue distribution in nude mice xenografted with human colon carcinoma.

Authors:  G T Rogers; R B Pedley; J Boden; P J Harwood; K D Bagshawe
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

Review 5.  Microbial cytosine deaminase is a programmable anticancer prodrug mediating enzyme: antibody, and gene directed enzyme prodrug therapy.

Authors:  Ashraf S A El-Sayed; Nabil Z Mohamed; Marwa A Yassin; Mahmoud M Amer; Reyad El-Sharkawy; Nesma El-Sayed; Mostafa G Ali
Journal:  Heliyon       Date:  2022-09-16

6.  Inactivation and clearance of an anti-CEA carboxypeptidase G2 conjugate in blood after localisation in a xenograft model.

Authors:  S K Sharma; K D Bagshawe; P J Burke; R W Boden; G T Rogers
Journal:  Br J Cancer       Date:  1990-05       Impact factor: 7.640
  6 in total

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