| Literature DB >> 3740405 |
E S Kempner, J H Miller, M J McCreery.
Abstract
The radiation sensitivity of glycoproteins is shown to depend only on the protein portion of the molecule. An artificially created glycoprotein containing glucose-6-phosphate dehydrogenase observes this rule as well as natural enzymes and receptors containing from 2 to 50% carbohydrate. No exceptions have been found. Radiation damage to carbohydrates occurs close to the site of the primary ionization, with little spread of damage into attached polypeptides.Entities:
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Year: 1986 PMID: 3740405 DOI: 10.1016/0003-2697(86)90165-x
Source DB: PubMed Journal: Anal Biochem ISSN: 0003-2697 Impact factor: 3.365