Literature DB >> 373922

High-dose methotrexate with citrovorum factor rescue in non-small-cell lung cancer.

F A Greco, M F Fer, R L Richardson, K R Hande, C J Van Boxtel, R K Oldham.   

Abstract

Nineteen patients with non-small-cell carcinoma of the lung were treated with high-dose methotrexate and leucovorin rescue. Two partial responses (10.5%) were observed, lasting 13 and 17 weeks. Toxicity was acceptable. It is concluded that the occasional benefit of high-dose methotrexate with leucovorin rescue at this dose and according to the schedule described for these patients does not warrant further study.

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Year:  1978        PMID： 373922     DOI： 10.1007/bf00257159

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  12 in total

1.  Third national cancer survey: incidence data.

Authors: 
Journal:  Natl Cancer Inst Monogr       Date:  1975-03

2.  Estimation of the antileukemic potency of the antimetabolite aminopterin, administered alone and in combination with citrovorum factor or folic acid.

Authors:  A GOLDIN; N MANTEL; S W GREENHOUSE; J M VENDITTI; S R HUMPHREYS
Journal:  Cancer Res       Date:  1953-12       Impact factor: 12.701

Review 3.  Advances in small cell bronchogenic carcinoma.

Authors:  P A Bunn; M H Cohen; D C Ihde; B E Fossieck; M J Matthews; J D Minna
Journal:  Cancer Treat Rep       Date:  1977 May-Jun

4.  Treatment of oat cell carcinoma of the lung: complete remissions, acceptable complications, and improved survival.

Authors:  F A Greco; R L Richardson; S F Schulman; S Stroup; R K Oldham
Journal:  Br Med J       Date:  1978-07-01

5.  "Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.

Authors:  J R Bertino
Journal:  Semin Oncol       Date:  1977-06       Impact factor: 4.929

6.  Adjuvant methotrexate and citrovorum-factor treatment of osteogenic sarcoma.

Authors:  N Jaffe; E Frei; D Traggis; Y Bishop
Journal:  N Engl J Med       Date:  1974-11-07       Impact factor: 91.245

7.  Methotrexate therapy of head and neck cancer: improvement in therapeutic index by the use of leucovorin "rescue".

Authors:  R L Capizzi; R C DeConti; J C Marsh; J R Bertino
Journal:  Cancer Res       Date:  1970-06       Impact factor: 12.701

8.  The mechanism of action of methotrexate. II. Augmentation by vincristine of inhibition of deoxyribonucleic aic synthesis by methotrexate in Ehrlich ascites tumor cells.

Authors:  I D Goldman; M J Fyfe
Journal:  Mol Pharmacol       Date:  1974-03       Impact factor: 4.436

9.  Platinum-based polychemotherapy versus dianhydrogalactitol in advanced non-small cell lung cancer.

Authors:  R T Eagan; J N Ingle; S Frytak; J Rubin; L K Kvols; D T Carr; D T Coles; J R O'Fallon
Journal:  Cancer Treat Rep       Date:  1977-10

10.  Competitive protein binding assay for methotrexate.

Authors:  C E Myers; M E Lippman; H M Elliot; B A Chabner
Journal:  Proc Natl Acad Sci U S A       Date:  1975-09       Impact factor: 11.205
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  1 in total

1.  Combination chemotherapy (high-dose methotrexate with citrovorum factor rescue, mechlorethamine, and procarbazine) in non-small cell lung cancer.

Authors:  R R Bhasin; C P Nogeirie
Journal:  Cancer Chemother Pharmacol       Date:  1983       Impact factor: 3.333
  1 in total

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