Literature DB >> 3738909

Regulatory effects of gastrin and secretin on carcinomas of the stomach and colon.

J Tanaka, T Yamaguchi, T Takahashi, N Ogata, K Bando, K Koyama.   

Abstract

Gastrin (10 micrograms/ml) enhanced 14C-leucine uptake in cultured tissue of stomach and colon carcinomas and content of 14C-labelled protein in the medium was increased. One of 2 stomach and one of 3 colon carcinomas transplanted into nude mice were enhanced in growth by pentagastrin injected in a dose of 250 micrograms/kg every day. On the other hand, secretin (100 U/kg) inhibited the trophic action of pentagastrin.

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Year:  1986        PMID： 3738909     DOI： 10.1620/tjem.148.459

Source DB:  PubMed          Journal:  Tohoku J Exp Med        ISSN： 0040-8727            Impact factor:   1.848


  5 in total

Review 1.  The risk of large bowel cancer after partial gastrectomy for benign ulcer disease.

Authors:  G Lundegårdh; H O Adami; C Helmick; M Zack
Journal:  Ann Surg       Date:  1990-12       Impact factor: 12.969

2.  Growth-promoting effects of gastrin on mouse colon cancer cells in vitro: absence of autocrine effects.

Authors:  Y S Guo; M Baijal; G F Jin; J C Thompson; C M Townsend; P Singh
Journal:  In Vitro Cell Dev Biol       Date:  1990-09

3.  Secretin-receptor and secretin-receptor-variant expression in gastrinomas: correlation with clinical and tumoral features and secretin and calcium provocative test results.

Authors:  Scott H Long; Marc J Berna; Michelle Thill; Andrea Pace; Tapas K Pradhan; K Martin Hoffmann; Jose Serrano; Robert T Jensen
Journal:  J Clin Endocrinol Metab       Date:  2007-08-21       Impact factor: 5.958

4.  Effect of endogenous hypergastrinemia on carcinogenesis in the rat esophagus.

Authors:  Y Karaki; K Shimazaki; M Okamoto; H Ookami; M Fujimaki
Journal:  Surg Today       Date:  1996       Impact factor: 2.549

5.  Polyamine levels and gastrin receptors in colon cancers.

Authors:  J R Upp; R Saydjari; C M Townsend; P Singh; S C Barranco; J C Thompson
Journal:  Ann Surg       Date:  1988-06       Impact factor: 12.969
  5 in total

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