| Literature DB >> 373792 |
W Bounds, M Vessey, P Wiggins.
Abstract
Fifty-five women using Loestrin-20 (20 microgram ethinyl oestradiol and 1 mg norethisterone acetate) as an oral contraceptive have been compared with a like number using Microgynon-30 (30 microgram ethinyl oestradiol and 150 microgram levonorgestrel) in a randomized, double-blind trial. Despite the small sample size, the main finding in the trial is clear-cut; Loestrin-20 provides poor cycle control and is thus less acceptable as an oral contraceptive than Microgynon-30. Although there is also a suggestion that Loestrin-20 may be less effective than Microgynon-30, the difference in the accidental pregnancy rates is not statistically significant.Entities:
Keywords: Amenorrhea; Bleeding; Comparative Studies; Contraception; Contraceptive Effectiveness; Contraceptive Methods--side effects; Developed Countries; Diseases; England; Europe; Family Planning; Menstruation Disorders; Metrorrhagia; Northern Europe; Oral Contraceptives, Low-dose--side effects; Oral Contraceptives--side effects; Research Methodology; Signs And Symptoms; Studies; United Kingdom; Use-effectiveness; Western Europe
Mesh：
Substances：
Year: 1979 PMID： 373792 DOI： 10.1111/j.1471-0528.1979.tb11263.x
Source DB: PubMed Journal: Br J Obstet Gynaecol ISSN： 0306-5456