| Literature DB >> 3736902 |
Abstract
Malignant brain tumors respond poorly to chemotherapy. This therapeutic resistance is the result of the marked heterogeneity of malignant gliomas in vivo and in vitro. Different factors, as specific markers, DNA distribution curves, morphology, chromosomal constitution, invasiveness and growth characteristics are considered for the understanding of the biology of malignant brain tumors. A better knowledge of this biology should provide new chemotherapeutic strategies.Entities:
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Year: 1986 PMID: 3736902 DOI: 10.1007/bf01743050
Source DB: PubMed Journal: Neurosurg Rev ISSN: 0344-5607 Impact factor: 3.042