Literature DB >> 3736902

The future of chemotherapy in malignant brain tumors.

L Calliauw, G Sieben.   

Abstract

Malignant brain tumors respond poorly to chemotherapy. This therapeutic resistance is the result of the marked heterogeneity of malignant gliomas in vivo and in vitro. Different factors, as specific markers, DNA distribution curves, morphology, chromosomal constitution, invasiveness and growth characteristics are considered for the understanding of the biology of malignant brain tumors. A better knowledge of this biology should provide new chemotherapeutic strategies.

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Year:  1986        PMID: 3736902     DOI: 10.1007/bf01743050

Source DB:  PubMed          Journal:  Neurosurg Rev        ISSN: 0344-5607            Impact factor:   3.042


  16 in total

1.  The distribution of nuclear DNA from human brain-tumor cells.

Authors:  T Hoshino; K Nomura; C B Wilson; K D Knebel; J W Gray
Journal:  J Neurosurg       Date:  1978-07       Impact factor: 5.115

2.  The influence of AZQ on the DNA distribution of human cerebral tumours in short-term culture.

Authors:  G Sieben; L Calliauw; P van Oostveldt; H Roels
Journal:  Eur J Cancer Clin Oncol       Date:  1985-02

3.  Heterogeneous response to chemotherapy of human gliomas grown in nude mice and as clones in vitro.

Authors:  W R Shapiro; W A Yung; G A Basler; J R Shapiro
Journal:  Cancer Treat Rep       Date:  1981

4.  Vitamin E increases the growth inhibitory and differentiating effects of tumor therapeutic agents on neuroblastoma and glioma cells in culture.

Authors:  K N Prasad; J Edwards-Prasad; S Ramanujam; A Sakamoto
Journal:  Proc Soc Exp Biol Med       Date:  1980-06

Review 5.  Review of basic concepts of cell kinetics as applied to brain tumors.

Authors:  T Hoshino; C B Wilson
Journal:  J Neurosurg       Date:  1975-02       Impact factor: 5.115

6.  Evaluation of CCNU, VM-26 plus CCNU, and procarbazine in supratentorial brain gliomas. Final evaluation of a randomized study. European Organization for Research on Treatment of Cancer (EORTC) Brain Tumor Group.

Authors: 
Journal:  J Neurosurg       Date:  1981-07       Impact factor: 5.115

7.  Human brain in tissue cultures. VI. Presence of glial fibrillary acidic protein in subcultivated human fetal brain cells as demonstrated by immunofluorescent and immunoperoxidase staining.

Authors:  D H Gilden; I Molenaar; M Devlin; L Eng; Z Wroblewska
Journal:  Acta Neuropathol       Date:  1981       Impact factor: 17.088

8.  Characterization of an established human malignant glioma cell line: LN-18.

Authors:  A C Diserens; N de Tribolet; A Martin-Achard; A C Gaide; J F Schnegg; S Carrel
Journal:  Acta Neuropathol       Date:  1981       Impact factor: 17.088

9.  Invasion of rat neurogenic cell lines in embryonic chick heart fragments in vitro.

Authors:  L I de Ridder; O D Laerum
Journal:  J Natl Cancer Inst       Date:  1981-04       Impact factor: 13.506

Review 10.  The biology of malignant gliomas--a comprehensive survey.

Authors:  R D McComb; D D Bigner
Journal:  Clin Neuropathol       Date:  1984 May-Jun       Impact factor: 1.368

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  1 in total

1.  The effects of local and systemic interferon beta (Fiblaferon) on supratentorial malignant cerebral glioma--a phase II study.

Authors:  K R von Wild; T H Knocke
Journal:  Neurosurg Rev       Date:  1991       Impact factor: 3.042

  1 in total

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