Literature DB >> 373646

A clinical comparison of beclomethasone dipropionate delivered by pressurised aerosol and as a powder from a rotahaler.

A T Edmunds, S McKenzie, M Tooley, S Godfrey.   

Abstract

14 children with severe asthma were studied for 2 months in a double-blind cross-over trial to compare the efficacy of beclomethasone dipropionate delivered as an aerosol and as a powder from a rotahaler. Inhalation via the aerosol was satisfactory in 13 patients, each of whom used the rotahaler correctly. Younger children preferred to use the rotahaler. Comparison of daily symptoms, twice daily peak expiratory flow rate (PEFR), and use of salbutamol during the 2 months of the trial showed that control of asthma was equally good, irrespective of the device used to deliver active beclomethasone.

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Year:  1979        PMID： 373646      PMCID： PMC1545230          DOI： 10.1136/adc.54.3.233

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  4 in total

1.  Treatment of childhood asthma for 13 months and longer with beclomethasone dipropionate aerosol.

Authors:  S Godfrey; P König
Journal:  Arch Dis Child       Date:  1974-08       Impact factor: 3.791

2.  Assessment of the child with asthma.

Authors:  N Connolly; S Godfrey
Journal:  J Asthma Res       Date:  1970-09

3.  Clinical and physiological assessment of asthmatic children treated with beclomethasone dipropionate.

Authors:  J Lovera; D M Cooper; C Collins-Williams; H Levison; J D Bailey; R P Orange
Journal:  J Allergy Clin Immunol       Date:  1976-02       Impact factor: 10.793

4.  Beclomethasone dipropionate steriod aerosol in treatment of perennial allergic asthma in children.

Authors:  H M Brown; G Storey
Journal:  Br Med J       Date:  1973-07-21
  4 in total
  9 in total

1.  Systematic review of clinical effectiveness of pressurised metered dose inhalers versus other hand held inhaler devices for delivering corticosteroids in asthma.

Authors:  D Brocklebank; J Wright; C Cates
Journal:  BMJ       Date:  2001-10-20

Review 2.  Beclomethasone at different doses for chronic asthma (review).

Authors:  N Adams; J Bestall; P Jones
Journal:  Cochrane Database Syst Rev       Date:  2001

Review 3.  Inhaler devices for the treatment of asthma and chronic obstructive airways disease (COPD).

Authors:  J Wright; D Brocklebank; F Ram
Journal:  Qual Saf Health Care       Date:  2002-12

4.  Controlled trial of budesonide given by the nebuhaler in preschool children with asthma.

Authors:  J G Gleeson; J F Price
Journal:  BMJ       Date:  1988-07-16

Review 5.  Beclomethasone dipropionate. A reappraisal of its pharmacodynamic properties and therapeutic efficacy after a decade of use in asthma and rhinitis.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1984-08       Impact factor: 9.546

6.  Nebulised beclomethasone dipropionate suspension.

Authors:  M S Webb; A D Milner; E J Hiller; R L Henry
Journal:  Arch Dis Child       Date:  1986-11       Impact factor: 3.791

7.  Inhaled beclomethasone and oral candidiasis.

Authors:  N J Shaw; A T Edmunds
Journal:  Arch Dis Child       Date:  1986-08       Impact factor: 3.791

8.  Nebulised beclomethasone dipropionate in preschool asthma.

Authors:  J Storr; C A Lenney; W Lenney
Journal:  Arch Dis Child       Date:  1986-03       Impact factor: 3.791

Review 9.  The Diskus: a review of its position among dry powder inhaler devices.

Authors:  H Chrystyn
Journal:  Int J Clin Pract       Date:  2007-06       Impact factor: 2.503
  9 in total

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