Literature DB >> 3735427

Tubulin mRNAs of Trypanosoma brucei.

M Imboden, B Blum, T DeLange, R Braun, T Seebeck.   

Abstract

The tubulin genes of Trypanosoma brucei are located in a single, tightly packed cluster of ten tandemly arranged alternating alpha and beta-genes. No tubulin genes are detected outside the clustered array. Therefore, the cluster can be assumed to be the locus of tubulin gene expression. Single bands of alpha and beta-tubulin mRNAs are observed in cultured procyclic as well as in bloodstream trypanosomes. Both alpha and beta-tubulin mRNAs have distinct 5' termini, which carry a 35-nucleotide mini-exon sequence. The 3' termini of both mRNA populations are heterogeneous.

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Year:  1986        PMID: 3735427     DOI: 10.1016/0022-2836(86)90163-4

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  13 in total

1.  RNA turnover in Trypanosoma brucei.

Authors:  B Ehlers; J Czichos; P Overath
Journal:  Mol Cell Biol       Date:  1987-03       Impact factor: 4.272

2.  Disruption of a gene encoding a novel mitochondrial DEAD-box protein in Trypanosoma brucei affects edited mRNAs.

Authors:  A Missel; A E Souza; G Nörskau; H U Göringer
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

3.  Permeable trypanosome cells as a model system for transcription and trans-splicing.

Authors:  E Ullu; C Tschudi
Journal:  Nucleic Acids Res       Date:  1990-06-11       Impact factor: 16.971

4.  Tubulin diversity in trophozoites of Giardia lamblia.

Authors:  Loraine Campanati; Helmut Troester; Luiz Henrique Monteiro-Leal; Herbert Spring; Michael F Trendelenburg; Wanderley de Souza
Journal:  Histochem Cell Biol       Date:  2003-04-10       Impact factor: 4.304

5.  A 60-kDa cytoskeletal protein from Trypanosoma brucei brucei can interact with membranes and with microtubules.

Authors:  T Seebeck; V Küng; T Wyler; M Müller
Journal:  Proc Natl Acad Sci U S A       Date:  1988-02       Impact factor: 11.205

6.  The common 5' terminal sequence on trypanosome mRNAs: a target for anti-messenger oligodeoxynucleotides.

Authors:  A W Cornelissen; M P Verspieren; J J Toulmé; B W Swinkels; P Borst
Journal:  Nucleic Acids Res       Date:  1986-07-25       Impact factor: 16.971

7.  Polycistronic transcripts in trypanosomes and their accumulation during heat shock: evidence for a precursor role in mRNA synthesis.

Authors:  M L Muhich; J C Boothroyd
Journal:  Mol Cell Biol       Date:  1988-09       Impact factor: 4.272

8.  Temporal order of RNA-processing reactions in trypanosomes: rapid trans splicing precedes polyadenylation of newly synthesized tubulin transcripts.

Authors:  E Ullu; K R Matthews; C Tschudi
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272

9.  Genomic and transcriptional linkage of the genes for calmodulin, EF-hand 5 protein, and ubiquitin extension protein 52 in Trypanosoma brucei.

Authors:  S Wong; T H Morales; J E Neigel; D A Campbell
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272

10.  Transcription of the intergenic regions of the tubulin gene cluster of Trypanosoma brucei: evidence for a polycistronic transcription unit in a eukaryote.

Authors:  M A Imboden; P W Laird; M Affolter; T Seebeck
Journal:  Nucleic Acids Res       Date:  1987-09-25       Impact factor: 16.971

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