Literature DB >> 3734346

[A case of hepatic and splenic peliosis occurring in the puerperium after normal pregnancy].

L M Patricot, M Dumont, J P Duvernois, J Baulieux, A Mercatello.   

Abstract

The authors report a case of Peliosis of the liver and of the spleen that occurred at term after a normal pregnancy that lasted 38 weeks. The delivery was complicated by amniotic infection with hemorrhagic shock and uterine inertia that gave rise to the need for a sub-total hysterectomy in order to stop the bleeding. The progress of the case was made worse by the development of the disseminated intra-vascular coagulation syndrome with septicaemia and pulmonary oedema. When the operation was carried out to stop the bleeding it was noted that the liver was enlarged, hard, smooth and dark in colour and the histological specimen showed a major degree of Peliosis hepatis. The same lesions were found in the region of the spleen and a lymph node. The patient died 14 days after delivery of acute renal failure together with cerebral oedema and septic shock. The authors consider that the aetiology of the Peliosis could be due to hormone changes of pregnancy associated with septicaemia. The anatomical evolution of Peliosis hepatis to widespread necrosis of the parenchyma makes it possible to understand that the condition of diffuse intra-vascular coagulation will not improve in the presence of hepato-cellular insufficiency.

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Year:  1986        PMID: 3734346

Source DB:  PubMed          Journal:  J Gynecol Obstet Biol Reprod (Paris)        ISSN: 0150-9918


  2 in total

Review 1.  Pregnancy and vascular liver disease.

Authors:  Julien Bissonnette; François Durand; Emmanuelle de Raucourt; Pierre-François Ceccaldi; Aurélie Plessier; Dominique Valla; Pierre-Emmanuel Rautou
Journal:  J Clin Exp Hepatol       Date:  2015-01-06

2.  Peliosis hepatis: a complicating finding in a case of biliary colic.

Authors:  Lars Grønlykke; Britta Tarp; Stephen Hamilton Dutoit; Rune Wilkens
Journal:  BMJ Case Rep       Date:  2013-09-26
  2 in total

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