Literature DB >> 3732635

Acetate and citrate stimulate water and sodium absorption in the human jejunum.

D D Rolston, K J Moriarty, M J Farthing, M J Kelly, M L Clark, A M Dawson.   

Abstract

Using a standard perfusion technique, the organic anions acetate (50 mmol/l) and citrate (5 mmol/l) have been shown to stimulate absorption of water and sodium from the human jejunum. These observations may support further the rationale for including acetate or citrate in oral rehydration solutions for the treatment of acute diarrhoeal disease in humans.

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Year:  1986        PMID： 3732635     DOI： 10.1159/000199317

Source DB:  PubMed          Journal:  Digestion        ISSN： 0012-2823            Impact factor:   3.216


  10 in total

Review 1.  History and rationale of oral rehydration and recent developments in formulating an optimal solution.

Authors:  M J Farthing
Journal:  Drugs       Date:  1988       Impact factor: 9.546

2.  Effect of bicarbonate on efficacy of oral rehydration therapy: studies in an experimental model of secretory diarrhoea.

Authors:  E J Elliott; A J Watson; J A Walker-Smith; M J Farthing
Journal:  Gut       Date:  1988-08       Impact factor: 23.059

3.  The role of bicarbonate and base precursors in treatment of acute gastroenteritis.

Authors:  E J Elliott; J A Walker-Smith; M J Farthing
Journal:  Arch Dis Child       Date:  1987-01       Impact factor: 3.791

Review 4.  Experimental models for the investigation of water and solute transport in man. Implications for oral rehydration solutions.

Authors:  J B Leiper; R J Maughan
Journal:  Drugs       Date:  1988       Impact factor: 9.546

5.  Citrate and recurrent idiopathic calcium urolithiasis. A longitudinal pilot study on the metabolic effects of oral potassium citrate administered over the short-, medium- and long-term medication of male stone patients.

Authors:  P O Schwille; U Herrmann; C Wolf; I Berger; R Meister
Journal:  Urol Res       Date:  1992

6.  Evaluation of the efficacy of oral rehydration solutions using human whole gut perfusion.

Authors:  D D Rolston; S N Zinzuvadia; V I Mathan
Journal:  Gut       Date:  1990-10       Impact factor: 23.059

7.  Acetate uptake by intestinal brush border membrane vesicles.

Authors:  A J Watson; E A Brennan; M J Farthing; P D Fairclough
Journal:  Gut       Date:  1991-04       Impact factor: 23.059

8.  Absorption of a hypotonic oral rehydration solution in a human model of cholera.

Authors:  J B Hunt; A V Thillainayagam; S Carnaby; P D Fairclough; M L Clark; M J Farthing
Journal:  Gut       Date:  1994-02       Impact factor: 23.059

9.  Water and solute absorption from a new hypotonic oral rehydration solution: evaluation in human and animal perfusion models.

Authors:  J B Hunt; A V Thillainayagam; A F Salim; S Carnaby; E J Elliott; M J Farthing
Journal:  Gut       Date:  1992-12       Impact factor: 23.059

10.  Randomised double blind trial of hypotonic oral rehydration solutions with and without citrate.

Authors:  T Rautanen; E Salo; M Verkasalo; T Vesikari
Journal:  Arch Dis Child       Date:  1994-01       Impact factor: 3.791
  10 in total

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