Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

Literature DB >> 3732495

Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

Abstract

Biosynthesis of cantharidin in a blister beetle, Lytta polita, is effectively inhibited by 6-fluoromevalonate. Inhibition is attributed specifically to the fluorine substituent. Biochemical inhibition has not been demonstrated previously for an arthropod's defensive substance.

Entities: Chemical

Mesh：

Substances：

Year: 1986 PMID： 3732495 DOI： 10.1007/bf01941552

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

3 in total

1. Cantharidin: potent feeding deterrent to insects.

Authors: J E Carrel; T Eisner
Journal: Science Date: 1974-02-22 Impact factor: 47.728

2. [Identification of farnesol as an intermediate in the biosynthesis of cantharidin from mevalonolactone].

Authors: M G Peter; W D Woggon; H Schmid
Journal: Helv Chim Acta Date: 1977-12-14 Impact factor: 2.164

3. Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate.

Authors: J F Nave; H d'Orchymont; J B Ducep; F Piriou; M J Jung
Journal: Biochem J Date: 1985-04-01 Impact factor: 3.857

3 in total

7 in total

1. De Novo Transcriptome and Expression Profile Analysis to Reveal Genes and Pathways Potentially Involved in Cantharidin Biosynthesis in the Blister Beetle Mylabris cichorii.

Authors: Yi Huang; Zhongkang Wang; Shenfang Zha; Yu Wang; Wei Jiang; Yufeng Liao; Zhangyong Song; Zhaoran Qi; Youping Yin
Journal: PLoS One Date: 2016-01-11 Impact factor: 3.240

Cantharidin biosynthesis in a blister beetle: inhibition by 6-fluoromevalonate causes chemical disarmament.

1. Cantharidin: potent feeding deterrent to insects.

2. [Identification of farnesol as an intermediate in the biosynthesis of cantharidin from mevalonolactone].

3. Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate.

1. De Novo Transcriptome and Expression Profile Analysis to Reveal Genes and Pathways Potentially Involved in Cantharidin Biosynthesis in the Blister Beetle Mylabris cichorii.

2. Characterization of Juvenile Hormone Related Genes Regulating Cantharidin Biosynthesis in Epicauta chinensis.

3. Draft genomes of two blister beetles Hycleus cichorii and Hycleus phaleratus.

4. The Potential Organ Involved in Cantharidin Biosynthesis in Epicauta chinensis Laporte (Coleoptera: Meloidae).

5. Draft Genome of a Blister Beetle Mylabris aulica.

Review 6. Drug Discovery Insights from Medicinal Beetles in Traditional Chinese Medicine.

7. Male Accessory Glands of Blister Beetles and Cantharidin Release: A Comparative Ultrastructural Analysis.