Literature DB >> 3730846

Angular bundle kindling is accelerated in rats with a genetic predisposition to acoustic stimulus-induced seizures.

D D Savage, C E Reigel, P C Jobe.   

Abstract

Limbic kindling was examined in genetically epilepsy-prone (GEPR) and non-epileptic control rats. The early stage of kindling development was accelerated in both groups of GEPR rats compared to controls. Later stages of kindling were accelerated in GEPR-9 but not GEPR-3 rats. These results indicate that GEPR rats have an enhanced susceptibility to limbic kindling and suggest that limbic brain alterations may contribute to acceleration of the early stage kindling development in GEPR rats.

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Year:  1986        PMID： 3730846     DOI： 10.1016/0006-8993(86)90211-8

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  3 in total

1.  The genetically epilepsy-prone rat (GEPR).

Authors:  P C Jobe; P K Mishra; L E Adams-Curtis; V U Deoskar; K H Ko; R A Browning; J W Dailey
Journal:  Ital J Neurol Sci       Date:  1995 Feb-Mar

2.  Evaluation of local cerebral glucose utilization and the permeability of the blood-brain barrier in the genetically epilepsy-prone rat.

Authors:  A Saija; P Princi; R De Pasquale; G Costa; G B De Sarro
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

3.  Protein expression of small conductance calcium-activated potassium channels is altered in inferior colliculus neurons of the genetically epilepsy-prone rat.

Authors:  Prosper N'Gouemo; Robert P Yasuda; Carl L Faingold
Journal:  Brain Res       Date:  2009-02-27       Impact factor: 3.252
  3 in total

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