Literature DB >> 3729340

Lack of relevance of kinetic parameters for exocellular DD-peptidases to cephalosporin MICs.

D B Boyd, J L Ott.   

Abstract

MICs of a set of cephalosporins against a variety of gram-positive and gram-negative pathogens showed no strong correlations with the rate at which these inhibitors acylate or are deacylated by beta-lactam-sensitive DD-peptidases excreted by Streptomyces sp. strain R61 and Actinomadura sp. strain R39.

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Year:  1986        PMID： 3729340      PMCID： PMC284153          DOI： 10.1128/AAC.29.5.774

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  39 in total

1.  The structure of beta-lactamases.

Authors:  R P Ambler
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1980-05-16       Impact factor: 6.237

2.  ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

Authors:  B Jaurin; T Grundström
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

3.  Active sites of beta-lactamases. The chromosomal beta-lactamases of Pseudomonas aeruginosa and Escherichia coli.

Authors:  V Knott-Hunziker; S Petursson; G S Jayatilake; S G Waley; B Jaurin; T Grundström
Journal:  Biochem J       Date:  1982-03-01       Impact factor: 3.857

Review 4.  The mechanism of the irreversible antimicrobial effects of penicillins: how the beta-lactam antibiotics kill and lyse bacteria.

Authors:  A Tomasz
Journal:  Annu Rev Microbiol       Date:  1979       Impact factor: 15.500

5.  Substituent effects in cephalosporins as assessed by molecular orbital calculations, nuclear magnetic resonance, and kinetics.

Authors:  D B Boyd
Journal:  J Med Chem       Date:  1983-07       Impact factor: 7.446

6.  beta-Lactam antibiotics: geometrical requirements for antibacterial activities.

Authors:  N C Cohen
Journal:  J Med Chem       Date:  1983-02       Impact factor: 7.446

7.  Isolation by covalent affinity chromatography of the penicillin-binding components from membranes of Bacillus subtilis.

Authors:  P M Blumberg; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1972-12       Impact factor: 11.205

8.  Synthesis and structure-activity relationships of 7 beta-[2-(2-aminothiazol-4-yl)acetamido]cephalosporin derivatives. V. Synthesis and antibacterial activity of 7 beta-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-cephalosporin derivates and related compounds.

Authors:  M Ochiai; A Morimoto; T Miyawaki; Y Matsushita; T Okada; H Natsugari; M Kida
Journal:  J Antibiot (Tokyo)       Date:  1981-02       Impact factor: 2.649

9.  Configuration of the methoxyimino group and penetration ability of cefotaxime and its structural analogues.

Authors:  A Costa; G A Botta
Journal:  J Antibiot (Tokyo)       Date:  1983-08       Impact factor: 2.649

10.  The active centres in penicillin-sensitive enzymes.

Authors:  J M Ghuysen; J M Frère; M Leyh-Bouille; H R Perkins; M Nieto
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1980-05-16       Impact factor: 6.237
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