Literature DB >> 3728801

Home support of patients with end-stage malignant bowel obstruction using hydration and venting gastrostomy.

B Gemlo, A A Rayner, B Lewis, A Wong, C S Viele, J R Ungaretti, A A DeLorimier, D C Hohn.   

Abstract

Palliative terminal care of patients with malignant bowel obstruction is a major clinical and ethical challenge. These patients are often mentally alert and ambulatory, but are kept in the hospital for hydration, nasogastric suction, and pain control. Parenteral nutrition requires frequent metabolic monitoring, is expensive, and is ethically questionable. We have used an alternative method of home management for 27 patients who met the following criteria: inoperable bowel obstruction due to untreatable cancer, an estimated life expectancy of between 2 weeks and 3 months, and understanding of the goals and limits of therapy. Hydration was provided by 10 percent dextrose and electrolyte solutions administered as overnight infusions through long-term central venous catheters. Thirteen patients with complete bowel obstruction required a venting gastrostomy which, when connected to passive drainage, relieved nausea and vomiting. The mean duration of survival was 64 days (range 9 to 223 days). Acceptance by patients and families was excellent, although most acknowledged increased costs due to limited insurance coverage for outpatient care. Seven patients returned to the hospital for terminal care (average stay 3.2 days), and 20 chose to die at home. The mean daily expense for fluids and supplies was +73.50, with an overall cost decrease of $900,000 compared with inpatient care. Home support with fluids and gastric venting is a humane, cost-effective alternative to in-hospital care for selected patients.

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Year:  1986        PMID: 3728801     DOI: 10.1016/0002-9610(86)90155-8

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  10 in total

Review 1.  Medical management of intestinal obstruction in terminal care.

Authors:  C Frank
Journal:  Can Fam Physician       Date:  1997-02       Impact factor: 3.275

Review 2.  Home parenteral nutrition for people with inoperable malignant bowel obstruction.

Authors:  Anne Marie Sowerbutts; Simon Lal; Jana Sremanakova; Andrew Clamp; Chris Todd; Gordon C Jayson; Antje Teubner; Anne-Marie Raftery; Eileen J Sutton; Lisa Hardy; Sorrel Burden
Journal:  Cochrane Database Syst Rev       Date:  2018-08-10

Review 3.  The role of parenteral nutrition in patients with malignant bowel obstruction.

Authors:  Federico Bozzetti
Journal:  Support Care Cancer       Date:  2019-07-17       Impact factor: 3.603

4.  Palliative venting gastrostomy in patients with malignant bowel obstruction and ascites.

Authors:  Colette Shaw; Roland L Bassett; Patricia S Fox; Kathleen M Schmeler; Michael J Overman; Michael J Wallace; Sanjay Gupta; Alda Tam
Journal:  Ann Surg Oncol       Date:  2012-09-11       Impact factor: 5.344

5.  Percutaneous transgastric intestinal decompression: the management of malignant bowel obstruction without nasal intubation.

Authors:  M Shinoda; M Kojima; T Fukase; H Ueno; T Ogihara
Journal:  Surg Today       Date:  1994       Impact factor: 2.549

Review 6.  Surgical management of malignant bowel obstruction: strategies toward palliation of patients with advanced cancer.

Authors:  Robert DeBernardo
Journal:  Curr Oncol Rep       Date:  2009-07       Impact factor: 5.075

7.  Development of a core outcome set to use in the research and assessment of malignant bowel obstruction: protocol for the RAMBO study.

Authors:  Elin Baddeley; Alison Bravington; Miriam Johnson; David C Currow; Fliss Em Murtagh; Elaine Boland; George Obita; Annmarie Nelson; Kathy Seddon; Alfred Oliver; Simon Noble; Jason Boland
Journal:  BMJ Open       Date:  2020-06-28       Impact factor: 2.692

8.  Symptom burden and lived experiences of patients, caregivers and healthcare professionals on the management of malignant bowel obstruction: A qualitative systematic review.

Authors:  Elin Baddeley; Mala Mann; Alison Bravington; Miriam J Johnson; David Currow; Fliss E M Murtagh; Elaine G Boland; George Obita; Alfred Oliver; Kathy Seddon; Annmarie Nelson; Jason W Boland; Simon I R Noble
Journal:  Palliat Med       Date:  2022-03-08       Impact factor: 5.713

9.  Survival, Healthcare Utilization, and End-of-life Care Among Older Adults With Malignancy-associated Bowel Obstruction: Comparative Study of Surgery, Venting Gastrostomy, or Medical Management.

Authors:  Elizabeth J Lilley; John W Scott; Joel E Goldberg; Christy E Cauley; Jennifer S Temel; Andrew S Epstein; Stuart R Lipsitz; Brittany L Smalls; Adil H Haider; Angela M Bader; Joel S Weissman; Zara Cooper
Journal:  Ann Surg       Date:  2018-04       Impact factor: 13.787

10.  MASCC multidisciplinary evidence-based recommendations for the management of malignant bowel obstruction in advanced cancer.

Authors:  Ainhoa Madariaga; Jenny Lau; Arunangshu Ghoshal; Tomasz Dzierżanowski; Philip Larkin; Jacek Sobocki; Andrew Dickman; Kate Furness; Rouhi Fazelzad; Gregory B Crawford; Stephanie Lheureux
Journal:  Support Care Cancer       Date:  2022-03-10       Impact factor: 3.359

  10 in total

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