Literature DB >> 3728468

Average inbreeding or equilibrium inbreeding?

P W Hedrick.   

Abstract

The equilibrium inbreeding is always higher than the average inbreeding. For human populations with high inbreeding levels, the inbreeding equilibrium is more than 25% higher than the average inbreeding. Assuming no initial inbreeding in the population, the equilibrium inbreeding value is closely approached in 10 generations or less. A secondary effect of this higher inbreeding level is that the equilibrium frequency of recessive detrimental alleles is somewhat lower than expected using average inbreeding.

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Year:  1986        PMID: 3728468      PMCID: PMC1684843     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN: 0002-9297            Impact factor:   11.025


  1 in total

1.  Inbreeding in Tamil Nadu, South India.

Authors:  P S Rao; S G Inbaraj
Journal:  Soc Biol       Date:  1977
  1 in total
  1 in total

1.  Mitigating false-positive associations in rare disease gene discovery.

Authors:  Sebastian Akle; Sung Chun; Daniel M Jordan; Christopher A Cassa
Journal:  Hum Mutat       Date:  2015-10       Impact factor: 4.878

  1 in total

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