Literature DB >> 3727212

Studies of Cd, Zn and Cu levels in human kidney tumours and normal kidney.

A Feustel, R Wennrich, M Dittrich.   

Abstract

The distribution of Cd, Zn and Cu was analyzed in nuclear, mitochondrial and cytosol cellular fractions of renal tumours and normal surrounding kidney tissues by electrothermal atomic absorption spectrometry (AAS). The normal kidney tissues were separated into cortical and medullary parts. A significant decrease of the Cd-levels was found in all cellular fractions from normal kidney to tumour tissues (hypernephroma). The Zn values varied strongly. We noted a slight decrease of Zn levels in renal tumour. The Cu concentration in the nucleus of kidney tumours was significantly increased.

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Year:  1986        PMID： 3727212     DOI： 10.1007/bf00257895

Source DB:  PubMed          Journal:  Urol Res        ISSN： 0300-5623


  9 in total

1.  Mechanism for cadmium and zinc antagonism of copper metabolism.

Authors:  G W Evans; P F Majors; W E Cornatzer
Journal:  Biochem Biophys Res Commun       Date:  1970-09-10       Impact factor: 3.575

2.  Renal cadmium content in the West of Scotland.

Authors:  R Scott; E Aughey; M Reilly; C Cunningham; A McClelland; G S Fell
Journal:  Urol Res       Date:  1983

3.  Association of cadmium with renal cancer.

Authors:  L N Kolonel
Journal:  Cancer       Date:  1976-04       Impact factor: 6.860

4.  Histochemical changes in protein disulphide bonds in rat liver and kidney after chronic cadmium administration, and the possible relation to metallothionein.

Authors:  A F Morselt; D Broekaert; E J Jongstra-Spaapen; J H Copius-Peereboom-Stegeman
Journal:  Arch Toxicol       Date:  1984-09       Impact factor: 5.153

5.  Determination of the distribution of zinc and cadmium in cellular fractions of BPH, normal prostate and prostatic cancers of different histologies by atomic and laser absorption spectrometry in tissue slices.

Authors:  A Feustel; R Wennrich
Journal:  Urol Res       Date:  1984

6.  Copper and zinc levels in normal and malignant tissues.

Authors:  E J Margalioth; J G Schenker; M Chevion
Journal:  Cancer       Date:  1983-09-01       Impact factor: 6.860

7.  Zinc and cadmium concentration in prostatic carcinoma of different histological grading in comparison to normal prostate tissue and adenofibromyomatosis (BPH).

Authors:  A Feustel; R Wennrich; D Steiniger; P Klauss
Journal:  Urol Res       Date:  1982

8.  Zinc and cadmium in cell fractions of prostatic cancer tissues of different histological grading in comparison to BPH and normal prostate.

Authors:  A Feustel; R Wennrich
Journal:  Urol Res       Date:  1984

Review 9.  Role of cadmium in carcinogenesis with special reference to cancer of the prostate.

Authors:  M Piscator
Journal:  Environ Health Perspect       Date:  1981-08       Impact factor: 9.031
  9 in total
  1 in total

1.  Zinc transporter genes and urological cancers: integrated analysis suggests a role for ZIP11 in bladder cancer.

Authors:  Lang Wu; Kari G Chaffee; Alexander S Parker; Hugues Sicotte; Gloria M Petersen
Journal:  Tumour Biol       Date:  2015-04-23
  1 in total

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