Literature DB >> 3724967

On the composition and characteristics of microvessels isolated from the rabbit and bovine brain.

G Algers, B Karlsson, A Sellström.   

Abstract

Brain capillaries (microvessels) were isolated from the rabbit and bovine brain. Extensive morphological examinations were performed at the light and electron microscopical levels. The relative contribution of endothelium (52%), basal membrane (32%) and pericytes (16%) to the composition of the microvessel was assessed. The ability of the endothelium from bovine brains to maintain a membrane potential, i.e. to accumulate the lipophilic cation [3H]TPMP, was shown. The transmitter catabolizing enzymes MAO and AchE were shown to be, and COMT and GABA-T not to be associated with the microvessel fraction isolated from rabbits.

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Year:  1986        PMID: 3724967     DOI: 10.1007/bf00965335

Source DB:  PubMed          Journal:  Neurochem Res        ISSN: 0364-3190            Impact factor:   3.996


  26 in total

1.  Neuronal and glial systems for gamma-aminobutyric acid metabolism.

Authors:  A Sellström; L B Sjöberg; A Hamberger
Journal:  J Neurochem       Date:  1975-10       Impact factor: 5.372

2.  A SENSITIVE AND SPECIFIC ASSAY FOR THE ESTIMATION OF MONOAMINE OXIDASE.

Authors:  R J WURTMAN; J AXELROD
Journal:  Biochem Pharmacol       Date:  1963-12       Impact factor: 5.858

3.  Isolation of metabolically active capillaries from rat brain.

Authors:  G W Goldstein; J S Wolinsky; J Csejtey; I Diamond
Journal:  J Neurochem       Date:  1975-11       Impact factor: 5.372

4.  Ultrastructural evidence for central monoaminergic innervation of blood vessels in the paraventricular nucleus of the hypothalamus.

Authors:  L W Swanson; M A Connelly; B K Hartman
Journal:  Brain Res       Date:  1977-11-04       Impact factor: 3.252

5.  Measurement of the membrane potential of isolated nerve terminals by the lipophilic cation [3H]triphenylmethylphosphonium bromide.

Authors:  E Hansson; I Jacobson; R Venema; A Sellström
Journal:  J Neurochem       Date:  1980-03       Impact factor: 5.372

Review 6.  Neurogenic mechanisms in the cerebrovascular bed. Autonomic nerves, amine receptors and their effects on cerebral blood flow.

Authors:  L Edvinsson
Journal:  Acta Physiol Scand Suppl       Date:  1975

7.  A simple specific method for the determination of the hemoglobin content of tissue homogenates.

Authors:  S Marklund
Journal:  Clin Chim Acta       Date:  1979-03-01       Impact factor: 3.786

8.  Developmental patterns of catechol-O-methyltransferase in genetically different rat strains: enzymatic and immunochemical studies.

Authors:  D J Goldstein; R M Weinshilboum; J H Dunnette; C R Creveling
Journal:  J Neurochem       Date:  1980-01       Impact factor: 5.372

9.  Studies on the monoamine oxidase and catechol-O-methyltransferase of the rat cerebral microvessels.

Authors:  F M Lai; S Spector
Journal:  Arch Int Pharmacodyn Ther       Date:  1978-06

10.  Barrier mechanisms for neurotransmitter monoamines and their precursors at the blood-brain interface.

Authors:  J E Hardebo; C Owman
Journal:  Ann Neurol       Date:  1980-07       Impact factor: 10.422

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  1 in total

1.  Purification and characterization of metabolically active capillaries of the blood-brain barrier.

Authors:  L Dallaire; L Tremblay; R Béliveau
Journal:  Biochem J       Date:  1991-06-15       Impact factor: 3.857

  1 in total

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