Literature DB >> 3724960

Taurine and other free amino acids in the retina, vitreous, lens, iris-ciliary body, and cornea of the rat eye.

A A Heinämäki, A S Muhonen, R S Piha.   

Abstract

Levels of free amino acids were determined quantitatively in whole ocular tissues of the rat eye with aid of a sensitive amino acid analyzer. The tissues studied were the retina, vitreous, lens, iris-ciliary body, and cornea. The retina and lens contained a more concentrated free amino acid pool than other tissues. The neuroactive amino acids taurine. GABA, glutamic acid, aspartic acid, and glycine were clearly enriched in the retina. Taurine was the most abundant amino acid in all five tissues studied, and its high concentration in non-neural tissues, especially the lens, suggests that it must have other functions as well as neurotransmitter ones in the rat eye.

Entities:  

Mesh:

Substances:

Year:  1986        PMID: 3724960     DOI: 10.1007/bf00965323

Source DB:  PubMed          Journal:  Neurochem Res        ISSN: 0364-3190            Impact factor:   3.996


  18 in total

1.  Studies on the crystalline lens. IX. Quantitative analysis of free amino acids and related compounds.

Authors:  D V REDDY; V E KINSEY
Journal:  Invest Ophthalmol       Date:  1962-10

2.  The excitation and depression of spinal neurones by structurally related amino acids.

Authors:  D R CURTIS; J C WATKINS
Journal:  J Neurochem       Date:  1960-09       Impact factor: 5.372

3.  Absolute levels of some free amino acids in normal and biologically fractionated retinas.

Authors:  A I Cohen; M McDaniel; H Orr
Journal:  Invest Ophthalmol       Date:  1973-09

4.  Distribution of free amino acids and related compounds in ocular fluids, lens, and plasma of various mammalian species.

Authors:  D V Reddy
Journal:  Invest Ophthalmol       Date:  1967-10

5.  Studis on intraocular transport of taurine. I. Accumulation in rabbit ciliary body-iris preparation in vitro.

Authors:  D V Reddy
Journal:  Biochim Biophys Acta       Date:  1968-05

6.  Free amino acids in senile cataractous lenses: possible osmotic etiology.

Authors:  G W Barber
Journal:  Invest Ophthalmol       Date:  1968-10

7.  Eye lens nucleotides of different species of vertebrates.

Authors:  J Klethi; P Mandel
Journal:  Nature       Date:  1965-03-13       Impact factor: 49.962

8.  Taurine in development and aging of ocular tissues.

Authors:  K Gupta; R L Mathur
Journal:  Exp Eye Res       Date:  1982-05       Impact factor: 3.467

9.  Taurine in ocular tissues of vertebrate species.

Authors:  K Gupta; R L Mathur; L P Agarwal
Journal:  Exp Eye Res       Date:  1981-06       Impact factor: 3.467

10.  High affinity binding of L-glutamate to chick retinal membranes.

Authors:  A M López-Colomé
Journal:  Neurochem Res       Date:  1981-09       Impact factor: 3.996

View more
  11 in total

1.  Calcium waves in retinal glial cells.

Authors:  E A Newman; K R Zahs
Journal:  Science       Date:  1997-02-07       Impact factor: 47.728

2.  A 1H NMR metabolomic approach for the estimation of the time since death using aqueous humour: an animal model.

Authors:  Emanuela Locci; Matteo Stocchero; Antonio Noto; Alberto Chighine; Luca Natali; Pietro Emanuele Napoli; Roberto Caria; Fabio De-Giorgio; Matteo Nioi; Ernesto d'Aloja
Journal:  Metabolomics       Date:  2019-05-08       Impact factor: 4.290

3.  Taurine Transporter dEAAT2 is Required for Auditory Transduction in Drosophila.

Authors:  Ying Sun; Yanyan Jia; Yifeng Guo; Fangyi Chen; Zhiqiang Yan
Journal:  Neurosci Bull       Date:  2018-07-24       Impact factor: 5.203

4.  Prevention of lens protein glycation by taurine.

Authors:  P S Devamanoharan; A H Ali; S D Varma
Journal:  Mol Cell Biochem       Date:  1997-12       Impact factor: 3.396

5.  Molecular identification and cellular localisation of GSH synthesis, uptake, efflux and degradation pathways in the rat ciliary body.

Authors:  Bo Li; Ankita Umapathy; Loi Uyen Tran; Paul J Donaldson; Julie C Lim
Journal:  Histochem Cell Biol       Date:  2012-11-15       Impact factor: 4.304

Review 6.  Review: taurine: a "very essential" amino acid.

Authors:  Harris Ripps; Wen Shen
Journal:  Mol Vis       Date:  2012-11-12       Impact factor: 2.367

7.  GABA maintains the proliferation of progenitors in the developing chick ciliary marginal zone and non-pigmented ciliary epithelium.

Authors:  Henrik Ring; Suresh Kumar Mendu; Shahrzad Shirazi-Fard; Bryndis Birnir; Finn Hallböök
Journal:  PLoS One       Date:  2012-05-09       Impact factor: 3.240

8.  NMR spectroscopy of human eye tissues: a new insight into ocular biochemistry.

Authors:  Tomasz Kryczka; Edward Wylęgała; Dariusz Dobrowolski; Anna Midelfart
Journal:  ScientificWorldJournal       Date:  2014-11-26

9.  Taurine protects against retinal and optic nerve damage induced by endothelin-1 in rats via antioxidant effects.

Authors:  Natasha Najwa Nor Arfuzir; Renu Agarwal; Igor Iezhitsa; Puneet Agarwal; Sabrilhakim Sidek; Nafeeza Mohd Ismail
Journal:  Neural Regen Res       Date:  2018-11       Impact factor: 5.135

10.  Synthesis of taurine-fluorescein conjugate and evaluation of its retina-targeted efficiency in vitro.

Authors:  Meihong Huang; Jiaqi Song; Bingzheng Lu; Huizhi Huang; Yizhen Chen; Wei Yin; Wenbo Zhu; Xinwen Su; Chuanbin Wu; Haiyan Hu
Journal:  Acta Pharm Sin B       Date:  2014-11-20       Impact factor: 11.413

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.